… %, below the threshold of concern for drug passage via breast milk. This is the first reported
case of modafinil transfer into human breast milk. Given the drug's use in a variety of sleep …

… These benefits of human milk have prompted an increasing number of health care workers
… since the extent of passage into milk has not been studied for most drugs. Moreover, their …

… the drug in milk provides a robust way of assessing infant exposure. On this basis, our data
show that a nursing infant who continued to breast feed following a 6 mg SC maternal dose, …

… the passage of drugs into human milk. One historical approach still being used is the prediction
of the drug level in milk based on plasma concentration and using what is called the milk-…

… and quantitatively reflect drug distribution in human milk. This … of breast milk, necessitating
methods to better predict drug … family members in the passage of drugs across the mammary …

… milk and summarized the effect of pregnancy on placental and of breastfeeding on mammal
gland drug … and M:P ratios of individual ARVs by drug class. Finally, we discussed the major …

… accuracy of estimates for drug concentration in human milk. Some extrapolations, … , drug
physicochemistry and general disposition, and from data available on drug excretion in milk of a …

… plasma concentrations of approximately 300 µg/L in adults8, the passage to breast milk
is … in human breast milk, and metformin in human milk and plasma with UHPLC- …

… Because obtaining PK data is challenging during the early postpartum period and modeling
of drug passage into human breast milk has been limited, 22 we report the development of a …

Aims In breastfeeding women, anti‐epileptic therapy can lead to infant toxicities, even with
newer anti‐epileptic drugs such as levetiracetam. This study assessed levetiracetam …