A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases

FW Ojara, AN Kawuma, C Waitt - PLOS Neglected Tropical …, 2023 - journals.plos.org
drug concentrations in both plasma and breast milk enables the characterization of
plasma-to-breast milk drug transfer, which enables linking administered drug dose to breast milk

[图书][B] Drug Monitoring in Breast Milk: Novel Insights on Pharmacokinetics and Infant Exposure Estimates

S Delaney - 2018 - search.proquest.com
drugs are considered to be compatible with breastfeeding, inaccurate infant exposure predictions
of drugs in breast milk … were to investigate the safety of three drugs and their use during …

Development of an in vitro cell culture model to study milk to plasma ratios of therapeutic drugs

MA Athavale, A Maitra, S Patel, VR Bhate… - Indian Journal of …, 2013 - journals.lww.com
… of a drug to be transferred to milk is expressed as its M/P ratio ie, the concentration of a drug
in breast milk/… Conducting in vivo studies with all the commonly used therapeutic drugs is no …

Pharmacokinetics in lactating women: prediction of alprazolam transfer into milk.

CY Oo, RJ Kuhn, N Desai, CE Wright… - British journal of …, 1995 - Wiley Online Library
… Previously, we haveproposed a diffusion model to predict the transfer of drug into milk
Relationship between human milk lipid:ultrafiltrate and octanol:water partition coefficients. J …

Celecoxib in human milk: a case report

DC Knoppert, D Stempak, S Baruchel… - … The Journal of Human …, 2003 - Wiley Online Library
… This is the first published case report of celecoxib in the human breast milk of which we
are aware. We were fortunate in being able to obtain milk samples. Because of its impromptu …

Excretion of psychotropic drugs into breast milk: pharmacokinetic overview and therapeutic implications

O Spigset, S Hägg - CNS drugs, 1998 - Springer
… excretion of these drugs into breast milk and the … drugs, data are extremely sparse or even
lacking. Although all psychotropic drugs that have been studied are excreted into breast milk, …

Transfer of buprenorphine into breast milk and calculation of infant drug dose

S Lindemalm, P Nydert, JO Svensson… - Journal of Human …, 2009 - journals.sagepub.com
… (n-BUP), into human milk and to determine the drug dose and effects in exposed infants. …
for addiction, and (3) presence in breast milk and passage to the nursing child. We developed a …

Prediction of basic drug exposure in milk using a lactation model algorithm integrated within a physiologically based pharmacokinetic model

A Pansari, M Faisal, M Jamei… - … & Drug Disposition, 2022 - Wiley Online Library
… properties for modeling drug passage into milk and to enable the prediction of the milk-to-plasma
(M/P) ratio that can be used to predict drug exposure in the milk (Atkinson & Begg, 1990…

Investigations of the in vitro transport of human milk oligosaccharides by a Caco-2 monolayer using a novel high performance liquid chromatography-mass …

MJ Gnoth, S Rudloff, C Kunz, RKH Kinne - Journal of Biological Chemistry, 2001 - ASBMB
… Complex lactose-derived oligosaccharides belong to the main components of human milk
of human milk oligosaccharides over Caco-2 monolayers. Main human milk oligosaccharides (…

Levetiracetam in lactation: How much is excreted into human breast milk?

N Dinavitser, E Kohn, M Berlin… - British journal of …, 2022 - Wiley Online Library
Aims In breastfeeding women, anti‐epileptic therapy can lead to infant toxicities, even with
newer anti‐epileptic drugs such as levetiracetam. This study assessed levetiracetam …