… The concentration of acetylsalicylic acid in breast milk is also low or undetectable, which
indicates that drugs containing this compound are safe for infants if consumed infrequently and …

… Passage numbers were selected based on expression of … between passages 55 and 65.
HT-29 cells (HTB-38; ATCC) were obtained from ATCC. Cultures were used between passages …

… plasma AUC 0 – 24 ( ( μ g / mL ) · h ) A power calculation for sample size was not performed
as the primary aim of the study was to establish transfer of the study drugs into breast milk. …

… Here, we have discussed the ratios in light of individual drug properties and principles of
drug passage through membranes. Maternal characteristics such as smoking habits or body …

… were prepared in human milk or human serum. for the assay of milk or serum antibiotic …
Acidic drugs tend to pass less readily into milk than basic drugs (4). Cephalosporins and …

… Passive and active transport processes are involved in the transfer of many drugs into breast
milk. In vitro models of passive drug transfer identify drug protein binding, drug ionization, …

… Let us assume that the level of CPT-11 in human milk was 399 ng/mL on Day 2 and … drug
in human milk on that day. As an infant (5 months old) consumes about 1000 mL of human milk …

… of high-quality data on drug excretion into human milk for medications women take while …
still gaps in knowledge regarding drug passage into breast milk. Some innate challenges are …

… her bloodstream to her human milk, with MPA milk concentrations of 35 mg/… drug, its
metabolism and safety profile, the risk of higher drug exposures in neonates, owing to immature drug…

… The intestinal immune barrier is responsible for the passage and absorption of nutrients
but … For instance, capsaicin may improve the paracellular transport of drugs that are poorly …