Drug repurposing—an emerging strategy in cancer therapeutics

KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
repurposed as cancer therapeutics (Fig. 1). This review article also includes the clinical trial
status of repurposed drugs, … focused upon for the treatment of various cancer types (Table 1). …

Overcoming cancer therapeutic bottleneck by drug repurposing

Z Zhang, L Zhou, N Xie, EC Nice, T Zhang… - Signal transduction and …, 2020 - nature.com
drug repurposing, we present various promising repurposed non-oncology drugs for clinical
cancer … either mono- or drug combination therapy. We also summarize approaches used for …

Drug repurposing strategies for non-cancer to cancer therapeutics

S Singhal, P Maheshwari… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
… For the other categories of non-cancer drugs, drug development approaches may be … In
summary, drug repurposing has opened a new arena for the development of anticancer drugs as …

[HTML][HTML] Computer-aided drug repurposing for cancer therapy: approaches and opportunities to challenge anticancer targets

C Mottini, F Napolitano, Z Li, X Gao… - Seminars in cancer biology, 2021 - Elsevier
… We will discuss how in-silico drug repurposing has the promise to shortly improve our …
that drug repurposing will set more and more stage in the future cancer therapeutics scenario. …

Drug repurposing for breast cancer therapy: Old weapon for new battle

S Aggarwal, SS Verma, S Aggarwal… - Seminars in cancer biology, 2021 - Elsevier
… a major role in the drug development. This article describes … scenario of drug repurposing
for the breast cancer treatment. The … therapeutic areas, such as reusing ovarian cancer drug as …

Drug repurposing in cancer

L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
… In this review we will discuss a number of licensed drug that has the potential to be
repurposed as anti-cancer drugs both in cancer prevention and therapy and highlight some of the …

Drug combination and repurposing for cancer therapy: the example of breast cancer

AS Correia, F Gärtner, N Vale - Heliyon, 2021 - cell.com
… associated costs, drug repurposing and drug combinations are … of these therapeutic modalities
for breast cancer therapy is … cancer and, particularly, breast cancer and its therapy. Also, …

Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics

A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
… of drug repurposing. In the present review, we are focusing on principles and tools used for
drug repurposing as well … agents/drugs for their repurposing ability against human cancers. …

Giving drugs a second chance: overcoming regulatory and financial hurdles in repurposing approved drugs as cancer therapeutics

JJ Hernandez, M Pryszlak, L Smith, C Yanchus… - Frontiers in …, 2017 - frontiersin.org
… in 100+ ongoing Phase II and Phase III clinical trials as a cancer therapeutic (1). Ideal
candidates for drug repurposing are entities that have undergone clinical trials and have been …

[HTML][HTML] Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance

D Ajmeera, R Ajumeera - Genes & Diseases, 2024 - Elsevier
cancer stem cells and their clinical application for cancer treatment. Further, drug repurposing
and the combination of micronutrients that can target both cancers and cancer stem cells …