Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
… As has typically been the case drug repurposing programmes, the interest in metformin was
… were less likely to develop cancer compared to patients on other diabetes drugs [5]. This …
… were less likely to develop cancer compared to patients on other diabetes drugs [5]. This …
Drug repurposing for the treatment of acute myeloid leukemia
V Andresen, BT Gjertsen - Frontiers in Medicine, 2017 - frontiersin.org
… Also the heterogeneity of AML will likely demand a broader repertoire of therapeutic molecules.
Drug repurposing or repositioning represent a source for potential therapeutics with well-…
Drug repurposing or repositioning represent a source for potential therapeutics with well-…
[HTML][HTML] Drugs repurposed: An advanced step towards the treatment of breast cancer and associated challenges
JA Malik, S Ahmed, B Jan, O Bender… - Biomedicine & …, 2022 - Elsevier
… the drug repurposing with a major focus on breast cancer. BC is a division of cancer known
as … The sluggish progression in developing new therapeutic drugs is partly due to the safety …
as … The sluggish progression in developing new therapeutic drugs is partly due to the safety …
Drug repurposing in oncotherapeutics
A Patel - Drug repurposing: hypothesis, molecular aspects and …, 2020 - books.google.com
… or inhibition of proliferation in proper cell culture environment of different cancer cells [46–48].
Also, genetic expression study of drugs based on cell line can help in drug repurposing. …
Also, genetic expression study of drugs based on cell line can help in drug repurposing. …
Drug repurposing towards targeting cancer stem cells in pediatric brain tumors
… While majority of cancer cells within a … therapeutic agents prompting cancer recurrence
with time. This renders the need for novel targeted therapeutic approaches for “repurposed drugs…
with time. This renders the need for novel targeted therapeutic approaches for “repurposed drugs…
Looking at NSAIDs from a historical perspective and their current status in drug repurposing for cancer treatment and prevention
… indicate new therapeutic targets, thereby identifying novel therapeutic actions for already
approved medicines, which is called drug repurposing. The strategy of drug repurposing, also …
approved medicines, which is called drug repurposing. The strategy of drug repurposing, also …
Revitalizing Cancer Treatment: Exploring the Role of Drug Repurposing
RR Malla, S Viswanathan, S Makena, S Kapoor… - Cancers, 2024 - mdpi.com
… for established drugs. By examining the multifaceted landscape of drug repurposing, this
review aims to offer comprehensive insights into its potential to transform cancer therapeutics. …
review aims to offer comprehensive insights into its potential to transform cancer therapeutics. …
A database of drug repurposing clinical trials in oncology
P Pantziarka, L Vandeborne, G Bouche - Frontiers in Pharmacology, 2021 - frontiersin.org
… types to the exploration of non-cancer drugs as new cancer therapeutics (Pushpakom … -cancer
drugs as potential cancer therapeutics. To this end the list of drugs classed as repurposing …
drugs as potential cancer therapeutics. To this end the list of drugs classed as repurposing …
Targeting autophagy by antipsychotic phenothiazines: potential drug repurposing for cancer therapy
… However, despite the promising initial results, available cancer therapeutics have limitations
that hinder its clinical use or reduce its effectiveness. Although all currently available …
that hinder its clinical use or reduce its effectiveness. Although all currently available …
Adopting drug repurposing to overcome drug resistance in cancer
E Shankar, V Subramaniam… - Frontiers in Cell and …, 2023 - frontiersin.org
… several therapeutics, but the entire process is tedious. Drug repurposing, also called drug
… opportunities to use approved or investigational drugs that are outside the scope of the …
… opportunities to use approved or investigational drugs that are outside the scope of the …