… of drug resistant TB, the use of individualized MDR-TB treatment regimens resulted in poor
treatment … Current guidelines for drug resistant TB management are based on expert opinion …

… multidrug-resistant tuberculosis (MDRTB). We present a new mathematical model (the
amplifier … -MDR) strains of drug-resistant Mycobacterium tuberculosis. We reconstruct possible …

… In conclusion, our study demonstrated a high risk of amplification of drug resistance among
patients treated using standard DOTS regimens. These results indicate that, in areas with …

… Previous data on drug resistance among previously treated patients with TB in Uganda are
… associated with drug resistance among treatment-experienced patients with TB in Kampala, …

… treatment regimens, thereby accelerating the development of MDR-TB through drug-specific
resistance amplification… use of TB drugs accounts for initial emergence of drug resistance.11 …

… control drug-susceptible (DS) and multi-drug resistant (MDR) TB. In this study, we developed
a two strain TB mathematical model with amplification and fit it to the Bangladesh TB data …

… of latent and active tuberculosis and rapid detection of drug resistance, specifically, tests that
… by Mycobacterium tuberculosis antigens, nucleic acid amplification for identification of M. …

… Drug resistance amplification and transmission We observed higher proportions of drug
resistance amplification for INH compared to RIF for both the high DR-TB incidence settings we …

… One promising method is phage amplification technology in which mycobacteriophages (bacteriophages
specific for mycobacteria) are used as an indicator of the presence of viable M. …

… diagnosis of TB and anti-tuberculous drug resistance in clinical microbiology laboratories. …
complex and simultaneously detect genetic mutations related to drug resistance. Amplified …