[HTML][HTML] Understanding hepatitis C virus drug resistance: clinical implications for current and future regimens

DL Wyles, AF Luetkemeyer - Topics in antiviral medicine, 2017 - ncbi.nlm.nih.gov
… When available, NS5A resistance can have important clinical implications for treatment-naive
and -experienced individuals with HCV infection. NS5A resistance testing is recommended …

Impact of cancer metabolism on therapy resistanceClinical implications

AC Gonçalves, E Richiardone, J Jorge, B Polónia… - Drug Resistance …, 2021 - Elsevier
resistance to anticancer therapies. Furthermore, we report on the role of TME-mediated
intratumor metabolic heterogeneity in drug resistance and the reliance of many therapy-resistant

Antiviral drug resistance: mechanisms and clinical implications

L Strasfeld, S Chou - Infectious Disease Clinics, 2010 - id.theclinics.com
… Consequences of drug resistance range from toxicity inherent in use of second-line …
the mechanisms, implications, and management of resistance to antiviral drugs used to treat …

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

T Shibue, RA Weinberg - Nature reviews Clinical oncology, 2017 - nature.com
… limited by the development of drug resistance. Such acquired resistance is driven, in part, …
a possible mechanistic basis for anticancer drug resistance. In fact, accumulating evidence …

Cytomegalovirus drug resistance and clinical implications

SW Chou - Transplant Infectious Disease, 2001 - Wiley Online Library
… isolates often contain multiple resistance mutations. A limitation of genotypic assays is that
drug resistance and risk factors Much of our existing knowledge about CMV drug resistance

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement

J Domínguez, EC Boettger, D Cirillo… - … of tuberculosis and …, 2016 - ingentaconnect.com
resistance-associated mutations in drugs for which there is poor or unproven correlation
between phenotypic and clinical drug resistance … of drug resistance, the clinical implications of …

[HTML][HTML] Mechanisms of action and clinical implications of microRNAs in the drug resistance of gastric cancer

Y Liu, X Ao, G Ji, Y Zhang, W Yu, J Wang - Frontiers in Oncology, 2021 - frontiersin.org
… Some also exhibit great potential as novel biomarkers for predicting drug response to …
of drug resistance in GC progression. We also highlight the potential of drug resistance-related …

Clinical implications of multi-drug resistance in the intensive care unit

DR Snydman - Scand J Infect Dis, 1991 - Taylor & Francis
… However, the frequency of cross-resistance and the development of resistance to fJ-lactams …
, many clinicians are not generally aware of the clinical implications of cross-resistance. Addi…

Antiplatelet drug resistance: Molecular insights and clinical implications

CN Floyd, A Ferro - Prostaglandins & other lipid mediators, 2015 - Elsevier
… that are known to confer resistance. Here we present molecular insights into the mechanisms
for aspirin and clopidogrel resistance, with a discussion of their clinical implications. …

Molecular mechanisms and clinical implications of miRNAs in drug resistance of colorectal cancer

L Duan, W Yang, W Feng, L Cao… - Therapeutic …, 2020 - journals.sagepub.com
drug resistance in CRC. Certain of these miRNAs may thus be used as promising biomarkers
for predicting drug … We also discuss the potential role of drug resistance-related miRNAs as …