… resistance has been a culprit for colorectal cancer (CRC) treatment. Here, we review a
novel therapeutic approach using α-amanitin antibody-drug … and chemotherapy drugs, this …

… the emergence of drug resistance is … drug resistance in CRC patients in preclinical and
clinical studies, which may provide valuable directions for future in-depth study of drug resistance…

… novel therapeutic strategies to overcome drug resistance using small molecules, which can
… CRC drug resistance and the possible role of preventing or reversing CRC drug resistance …

… Drug resistance is thought to cause treatment failure in over 90% of patients with metastatic
cancer, while drug resistant … of drug resistance that may be relevant to colorectal cancer. We …

… cell-related signals mediate anti-cancer drug resistance in our established model, and that
the model is useful for investigating the mechanisms of drug resistance of CRC (Figure 3). …

Colorectal cancer (CRC) is a common malignancy with 1. 8 million cases in 2018. … for
cancer treatment and lncRNAs play a pivotal role in resistance acquisition for several drugs. …

… In conclusion, we identified candidate genes, gene sets and pathways related to drug
resistance in colorectal cancer, which warrant further investigation. The drug-resistant score …

… of cancer treatment over the past decades, drug resistance is still one of the major hurdles of
effective therapy for advanced colorectal cancer … ) may contribute to drug resistance in CRC. …

… drug resistance in CRC. Certain of these miRNAs may thus be used as promising biomarkers
for predicting drug … We also discuss the potential role of drug resistance-related miRNAs as …

… , Targeted therapy, Drug-resistance, Personalized medicine Core Tip: Efforts in cancer …
of the molecular mechanisms underlying colorectal cancer (CRC) resistance and metastasis. …