… , which are not killed by conventional cancer therapies. Lastly… drug resistant cancers, ways
to prevent the formation of drug … cancer progenitor cells or drug resistant cancer cells render …

… and molecular parameters of cancer cells and extrinsic environmental factors… drug resistance
in cancer have focused on the binary differences between intrinsic and acquired resistance…

… in the intrinsic and acquired resistance of cancer cells to current cancer therapies. We …
cancer cells during cancer progression that may contribute in a crucial manner to drug resistance …

… drug resistance may exist in cancer cells prior to therapies due to the presence of genetic
mutation(s) of genes involved in cancer cell … in cancer cell growth, survival and drug resistance …

… by which cells acquire pleiotropic drug resistance appears to … breast cancer cells. J Clin
Invest 70: 351-360, 1982. 28. … of resistance to methotrexate in human breast cancer cells: lack of …

… the extracellular environment has been shown to reverse drug resistance in chemoresistant
melanoma cancer cells and sensitize multi-drug resistant cells to cytotoxic drugs [102], [103]. …

… [55] found that in several drug-resistant cancer cell lines as well as in DNA from two
leukaemic patients who had developed drug resistance, gene rearrangements had occurred …

… and encouraged multiplicity in acquired cross-resistance. Additionally, we found that
secretome factors from PTX-resistant cancer cells with acquired crossresistance support a P-gp-…

… in intercellular adhesion was sufficient to confer drug resistance to tumor cells [14]. In su P
… -dependent resistance In human colon cancer cells: role of reduced drug accumulation and …

… Other models used paradigm prokaryotic organisms, such as Escherichia coli, in an effort
to detect mutations in drug-resistant cancer cells and investigate their role in drug …