Evidence for therapeutic drug monitoring of targeted anticancer therapies
B Gao, S Yeap, A Clements, B Balakrishnar… - Journal of Clinical …, 2012 - ascopubs.org
… adequately define systemic exposure of drugs that have a short … However, the newer
targeted anticancer therapies have … drugs, making it possible to estimate the steady-state drug …
targeted anticancer therapies have … drugs, making it possible to estimate the steady-state drug …
Current targets for anticancer drug discovery
… a promising strategy for anticancer therapy, intense efforts have … been established as a solid
target for anticancer therapy [35]. … therapy, eg less toxicity compared to standard anticancer …
target for anticancer therapy [35]. … therapy, eg less toxicity compared to standard anticancer …
Therapeutic drug monitoring of targeted anticancer therapy
LA Decosterd, N Widmer, K Zaman… - Biomarkers in …, 2015 - Future Medicine
… Their therapeutic use could however be optimized by … the therapeutic drug monitoring (TDM).
TDM can increase the probability of therapeutic responses to targeted anticancer therapies, …
TDM can increase the probability of therapeutic responses to targeted anticancer therapies, …
[HTML][HTML] Apoptosis: a target for anticancer therapy
CM Pfeffer, ATK Singh - International journal of molecular sciences, 2018 - mdpi.com
… common anticancer therapy, chemotherapy. Promising new anticancer therapies are
plant-derived compounds that exhibit anticancer activity through activating the apoptotic pathway. …
plant-derived compounds that exhibit anticancer activity through activating the apoptotic pathway. …
Understanding, recognizing, and managing toxicities of targeted anticancer therapies
GK Dy, AA Adjei - CA: a cancer journal for clinicians, 2013 - Wiley Online Library
… Thus, for targeted therapies with demonstrable clinical anticancer efficacy, treating physicians
have to be cognizant of the insidious onset of subacute to late toxicities associated with …
have to be cognizant of the insidious onset of subacute to late toxicities associated with …
[HTML][HTML] Mitosis-targeted anti-cancer therapies: where they stand
… , targeting the mitotic defects of cancer cells can still be useful in anti-cancer therapy. …
mitosis a valid point of intervention in anti-cancer therapy. It is widely regarded that antimitotics …
mitosis a valid point of intervention in anti-cancer therapy. It is widely regarded that antimitotics …
[PDF][PDF] Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
… available anticancer drugs that have collectively saved millions of life-years mediate therapeutic
… Here, we discuss the capacity of both conventional and targeted anticancer therapies to …
… Here, we discuss the capacity of both conventional and targeted anticancer therapies to …
Somatostatin receptor-targeted anti-cancer therapy
LC Sun, DH Coy - Current drug delivery, 2011 - ingentaconnect.com
… CANCER THERAPY Receptor-targeted drug delivery, an alternative chemotherapy approach,
… and increase the efficacy of treatment by targeting the specific receptor-expressing tumor …
… and increase the efficacy of treatment by targeting the specific receptor-expressing tumor …
The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?
CJ Desmet, DS Peeper - Cellular and Molecular Life Sciences CMLS, 2006 - Springer
… data on the suitability of Trks as anti-cancer therapeutic targets. Taken together, the vast …
as well as molecular basis for anti-cancer therapies targeting TrkB. The development of …
as well as molecular basis for anti-cancer therapies targeting TrkB. The development of …
Receptor tyrosine kinases: the main targets for new anticancer therapy
J Drevs, M Medinger, C Schmidt-Gersbach… - … drug targets, 2003 - ingentaconnect.com
… such drugs is to understand the targets that these agents should attack. In recent years a
number of promising new anticancer drugs have been developed which target intracellular …
number of promising new anticancer drugs have been developed which target intracellular …
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