A learning-based method for drug-target interaction prediction based on feature representation learning and deep neural network
J Peng, J Li, X Shang - BMC bioinformatics, 2020 - Springer
… We propose a learning-based method based on feature representation learning and deep
… Drug targets are special molecules that can bind to drugs and produce effects in cells, the …
… Drug targets are special molecules that can bind to drugs and produce effects in cells, the …
An end-to-end heterogeneous graph representation learning-based framework for drug–target interaction prediction
… ) is a powerful deep representation learning method for network data, … representation
learning-based framework, named EEG-DTI, to identify the interactions between drug and target. To …
learning-based framework, named EEG-DTI, to identify the interactions between drug and target. To …
Prediction of drug-target interactions based on multi-layer network representation learning
… multilayer network representation learning method for drug-target … learn the feature vectors
of drugs and targets. The feature vectors of the drug and the target are put into the drug-target …
of drugs and targets. The feature vectors of the drug and the target are put into the drug-target …
MultiDTI: drug–target interaction prediction based on multi-modal representation learning to bridge the gap between new chemical entities and known heterogeneous …
… In our joint representation learning framework, we take the … drugs, targets, side effects and
diseases as constraints, and map the sequence representations of drugs and targets to the …
diseases as constraints, and map the sequence representations of drugs and targets to the …
Prediction of drug–target interactions based on network representation learning and ensemble learning
… side effects of drugs. We propose a network representation learning method based on matrix
factorisation to learn low-dimensional vector representations of drug and protein nodes. On …
factorisation to learn low-dimensional vector representations of drug and protein nodes. On …
A novel method to predict drug-target interactions based on large-scale graph representation learning
… Consequently, we constructed a large-scale graph representation learning network to
learn the features of each node, as shown in Figure 2. In which Figure 2A is the drug-target …
learn the features of each node, as shown in Figure 2. In which Figure 2A is the drug-target …
GraphMS: drug target prediction using graph representation learning with substructures
… learning methods are also widely used in feature mapping [3], classification task [4] and disease
prediction [5]. Moreover, differentiable representation learning … Representation Learning …
prediction [5]. Moreover, differentiable representation learning … Representation Learning …
DeepGS: Deep representation learning of graphs and sequences for drug-target binding affinity prediction
… Then, we introduce the representation learning for drugs and targets, respectively (Sections
2.2∼2.3). Finally, we discuss the binding affinity prediction with DeepGS (Section 2.4). …
2.2∼2.3). Finally, we discuss the binding affinity prediction with DeepGS (Section 2.4). …
Hierarchical graph representation learning for the prediction of drug-target binding affinity
… drugs interact with targets that is beneficial for predictive accuracy. In this paper, we propose
a novel hierarchical graph representation learning … hierarchical graph learning architecture …
a novel hierarchical graph representation learning … hierarchical graph learning architecture …
Accurate prediction of molecular properties and drug targets using a self-supervised image representation learning framework
… of downstream task related to molecular representation learning for testing: molecular
property prediction, drug metabolism prediction, drug–protein binding prediction and antiviral …
property prediction, drug metabolism prediction, drug–protein binding prediction and antiviral …
相关搜索
- drug target interaction prediction
- drug target binding affinity prediction
- drug target interactions network representation
- graph representation drug target
- deep neural network drug target
- heterogeneous network drug target
- drug target interaction molecular representations
- target interactions graph representation learning method
- graph convolutional autoencoder drug target
- drug target interaction kernel learning
- drug target interactions deep learning framework
- drug target affinity protein knowledge
- graph attention network drug target
- feature representation learning drug target
- deep representation learning drug target
- ensemble learning drug target