… this kinase such as p68 protein kinase, DAI (Double stranded Activated Inhibitor), dsRNA-dependent
protein kinase, P1/eIF2α kinase … name, for Protein Kinase dsRNA-dependent [19]. …

… a complex set of proteins. One of the best known IFNinduced protein is the dsRNA-dependent
protein kinase (PKR), … Control of PKR protein kinase by hepatitis C virus nonstructural 5A …

… protein kinase from human cells to homogeneity and to characterize its enzymatic activity.'27""29'The
dsRNA-PK is a 68,000 A/r protein (… the protein kinase are detectable in control cells …

… translation and even inducing cellular apoptosis to debilitate virus … dsRNA-mediated events
is PKR (protein kinase RNA-dependent), an IFN-inducible serine/threonine protein kinase …

… role as a translational controlling factor, the double stranded RNA-dependent protein kinase
(PKR) … To define how PKR mediates NF-κB activation by dsRNA, we have used two different …

… The double stranded RNA-dependent protein kinase (PKR), in addition to its role as a
translational controlling factor, is a key transcriptional regulator exerting antiviral and antitumoral …

… As an IFN-induced, dsRNA-activated protein kinase that can control protein synthesis, PKR
is considered as one of the major players in the antiviral action of IFN. Indeed, a number of …

… Sequence of the site in the alpha subunit phosphorylated by the haem-controlled
repressor and by the double-stranded RNA-activated inhibitor. Eur J Biochem 166: 357–363. …

… synthesis is not the only pathway that is a target for regulation by PKR, and that the protein
kinase may control certain signal transduction and transcriptional events in uninfected cells. …

… synthesis also involve the dsRNA-… protein synthesis in lysates in the absence of dsRNA
(29, 30). Fig. also demonstrates that uninduced control ribosomes (-dsI) contain protein kinase …