The short, the long and the “ultra-long”: why duration of bronchodilator action matters in chronic obstructive pulmonary disease

KM Beeh, J Beier - Advances in therapy, 2010 - Springer
… Alongside the introduction of each new class of bronchodilator, longer duration of
bronchodilation has been achieved and more consistent improvements in lung function and patient-…

Bronchodilator responsiveness in patients with COPD

DP Tashkin, B Celli, M Decramer, D Liu… - European …, 2008 - Eur Respiratory Soc
… agents for periods exceeding their known duration of action (to avoid confounding by
residual effects of previous bronchodilator therapy), the performance of post-bronchodilator

Therapeutic responses in asthma and COPD: bronchodilators

JF Donohue - Chest, 2004 - Elsevier
bronchodilators are used “as needed” in asthma management, regular bronchodilator therapy
… Onset of ipratropium action was within 30 min, with peak response at 1 to 2 h and duration

Response to bronchodilators

C Shim - Clinics in chest medicine, 1989 - Elsevier
… of bronchodilator response is necessary to establish reversibility of airflow obstruction. It allows
monitoring of the efficacy of bronchodilator therapy … of bronchodilators and the duration of …

Bronchodilator reversibility in COPD

NA Hanania, BR Celli, JF Donohue, UJ Martin - Chest, 2011 - Elsevier
response to a short- or long-acting bronchodilator does not preclude subsequent benefit from
maintenance bronchodilator therapy.14, … has a shorter duration of action. The magnitude of …

[PDF][PDF] Bronchodilator therapy with metered-dose inhaler and spacer versus nebulizer in mechanically ventilated patients: comparison of magnitude and duration of …

AG Duarte, K Momii, A Bidani - Respiratory care, 2000 - academia.edu
… the action of inhaled bronchodilators in mechanically ventilated patients, we were interested
in evaluating the duration of bronchodilator response over 4 hours. We conjectured that …

Bronchodilator therapy: Comparison of acute response to three methods of administration

EH Chester, I Racz, PB Barlow, GL Baum - Chest, 1972 - Elsevier
… of other pulmonary function variables was generally similar to that of the VxR, but in several
patients the response was of lesser magnitude. The duration of response was variable from …

Effects of long-term bronchodilators in bronchiectasis patients with airflow limitation based on bronchodilator response at baseline

HJ Jeong, H Lee, KC Carriere, JH Kim… - … Journal of Chronic …, 2016 - Taylor & Francis
bronchodilator response (BDR) at baseline and the effect of long-term bronchodilator therapy
has … difference in the median duration of bronchodilator use between responders and poor …

Clinical pharmacology of bronchodilator medications

DM Williams, BK Rubin - Respiratory Care, 2018 - rc.rcjournal.com
… are major targets for bronchodilator therapy. Bronchodilation can be achieved through 2 …
and duration of response. These changes can be clinically relevant as they may limit the …

Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

DP Tashkin, GT Ferguson - Respiratory research, 2013 - Springer
… tiotropium was inadvisable, due to the shorter duration of bronchodilation provided by
salmeterol [76]. The Canadian Optimal Therapy of COPD trial investigated the impact of tiotropium …