IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies

AL Hardaway, I Podgorski - Future Medicinal Chemistry, 2013 - Taylor & Francis
inflammatory state, which is a consequence of an excess nutrient flux. This so-called metabolic
inflammation has deleterious effects on metabolic … levels of inflammatory cytokines and …

Hypertension, obesity, and inflammation: the complex designs of a deadly trio

AA Rizvi - Metabolic Syndrome and Related Disorders, 2010 - liebertpub.com
… the metabolic syndrome. The interplay of hypertension, insulin resistance, and obesity vastly
enhances the noxious influence of inflammation … and humoral dynamics in hypertension, a …

[HTML][HTML] The Synergistic Trio of Metabolic Master Regulators Sustaining a Vicious Circle of Pathological Processes in Post-Traumatic Stress Disorder

MV Kondashevskaya, KA Artemyeva… - Journal of Evolutionary …, 2024 - Springer
… on gastrointestinal factors that are dynamically involved in the … mast cells, whose synergistic
trio, according to our hypothesis, … only in inflammatory bowel diseases but also in metabolic

[HTML][HTML] Dynamic and systemic perspective in autism spectrum disorders: A change of gaze in research opens to a new landscape of needs and solutions

C Panisi, M Marini - Brain Sciences, 2022 - mdpi.com
inflammatory, metabolic, degenerative, and neoplastic diseases [35], as put forward by the
Developmental Origin of Health and Diseases Theory (DOHaD Theory) which suggests an …

[HTML][HTML] Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study

L Chen, SA Mir, AK Bendt, EWL Chua, K Narasimhan… - BMC medicine, 2023 - Springer
… are used as measures of metabolic health status and … metabolic diseases. With the advances
in high throughput mass spectrometry-based lipidomics methods, the diverse and dynamic

Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis

S Mazumder, S Bindu, R De, S Debsharma… - Life Sciences, 2022 - Elsevier
… Other IBD susceptibility gene mutations which have been found to affect mitochondrial
metabolism and … Metabolic stress in the form of self-perpetuating inflammation, misfolded protein …

[HTML][HTML] Metabolic hormones modulate macrophage inflammatory responses

MJ Batty, G Chabrier, A Sheridan, MC Gage - Cancers, 2021 - mdpi.com
… hormones in modulating macrophage inflammatory responses. In this review, we highlight
key metabolic hormones and summarise their influence on the inflammatory response of …

[HTML][HTML] The interplay between tissue niche and macrophage cellular metabolism in obesity

S Daemen, JD Schilling - Frontiers in immunology, 2020 - frontiersin.org
… This review will address the current knowledge on altered macrophage dynamics in … In
summary, although glucose metabolism is associated with classical inflammatory macrophage …

Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice

A Farini, L Tripodi, C Villa, F Strati… - EMBO molecular …, 2023 - embopress.org
… Since dystrophic muscles are sensed by infiltrating inflammatory cells and gut microbial
communities can cause immune dysregulation and metabolic syndrome, we sought to …

Increased microvascularization and vessel permeability associate with active inflammation in human atheromata

VR Taqueti, MF Di Carli, M Jerosch-Herold… - Circulation …, 2014 - Am Heart Assoc
dynamic contrast–enhanced magnetic resonance imaging (DCE-MRI), allow measurement
of metabolic … may not reflect the prevailing inflammatory activity. Indeed, mononuclear …