Plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk

R Mayeux, LS Honig, MX Tang, J Manly, Y Stern… - Neurology, 2003 - AAN Enterprises
… Our limited results with repeated samples indicate that the plasma levels of Aβ42 begin to
decrease soon after the diagnosis of AD has been established, which has been observed by …

Association of low plasma Aβ42/Aβ40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease

NR Graff-Radford, JE Crook, J Lucas… - Archives of …, 2007 - jamanetwork.com
… The results of the longitudinal study presented herein are, to our knowledge, the first to
indicate that the plasma Aβ42/Aβ40 ratio may be useful for identifying elderly white subjects who …

Blood-based biomarkers for Alzheimer's disease: plasma Aβ40 and Aβ42, and genetic variants

R Mayeux, N Schupf - Neurobiology of aging, 2011 - Elsevier
plasma Aβ40 and Aβ42 as diagnostic biomarkers as well as risk biomarkers. Review of recent
genome-wide association … : Down syndrome, familial Alzheimer's disease, and first degree …

Evaluation of plasma Aβ40 and Aβ42 as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

O Hansson, H Zetterberg, E Vanmechelen… - Neurobiology of …, 2010 - Elsevier
… that were longitudinally followed for several years provides no support for the usefulness
of plasma Aβ as a diagnostic marker for early AD. The lack of correlation between CSF and …

[HTML][HTML] Evolution of Aβ42 and Aβ40 levels and Aβ42/Aβ40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment

K Blennow, G De Meyer, O Hansson, L Minthon… - … of nutrition, health and …, 2009 - Elsevier
… precision, even for low Aβ42 plasma concentrations. Aβ40 and Aβ42 concentrations varied
… To our knowledge this is the first multicenter study on human plasma Aß determinations with …

Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Aβ42/Aβ40 and p‐tau

S Janelidze, S Palmqvist, A Leuzy… - Alzheimer's & …, 2022 - Wiley Online Library
… Institute on Aging-Alzheimer's Association study patients with … available plasma Aβ42/Aβ40,
plasma p-tau217, plasma NfL, … plasma Aβ42/Aβ40 and plasma p-tau217 with plasma NfL. In …

Elevation of the plasma Aβ 40/Aβ 42 ratio as a diagnostic marker of sporadic early-onset Alzheimer's disease

HJ Kim, KW Park, TE Kim, JY Im… - … of Alzheimer's …, 2015 - content.iospress.com
plasma levels of 40 , 42 , and the 40 / 42 ratio as biomarkers of AD in subjects
with earlyPlasma levels of 40 and 42 were measured using a sandwich enzyme-linked …

… simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease

H Shahpasand-Kroner, HW Klafki, C Bauer… - Alzheimer's Research & …, 2018 - Springer
… Neurochemical biomarkers in cerebrospinal fluid (CSF) and imaging biomarkers can
support the early diagnosis of Alzheimer’s disease (AD). In numerous studies, low CSF …

The efficacy of plasma biomarkers in early diagnosis of Alzheimer's disease

T Wang, S Xiao, Y Liu, Z Lin, N Su, X Li… - … journal of geriatric …, 2014 - Wiley Online Library
… of AD such as Aβ40, Aβ42, P-tau 181, T-tau, and the plasma pro-… plasma Aβ42 cannot
discriminate the aMCI or AD group from normal control group. Although, unlike Aβ42, Aβ40

Plasma Aβ42/40 ratio detects early stages of Alzheimer's disease and correlates with CSF and neuroimaging biomarkers in the AB255 study

V Perez-Grijalba, J Romero, P Pesini, L Sarasa… - … of Alzheimer's disease, 2019 - Springer
plasma Aβ42/40 ratio with increased risk of incident AD (17-19). Furthermore, we recently
showed an association between low total plasma Aβ42/… In this work, total in plasma Aβ42/Aβ40