Human embryonic stem cells: early hints on safety and efficacy

A Atala - The Lancet, 2012 - thelancet.com
In The Lancet, Steven Schwartz and colleagues1 report the first clinical experience of
patients treated with cells derived from human embryonic stem cells (hESCs). A patient with …

Controversies in cancer stem cells: targeting embryonic signaling pathways

N Takebe, SP Ivy - Clinical Cancer Research, 2010 - AACR
… Whether CSC niches are assembled early in embryogenesis, seized from other stem cells, …
-receptor combinations hints at the multitude of complex cellular downstream effects that are …

5 things to know before jumping on the iPS bandwagon: induced pluripotent stem cells look just like embryonic stem cells, but are easier to create and free of the …

D Cyranoski - Nature, 2008 - go.gale.com
cells, might see early application of iPS cells. Kyoto University's Jun Takahashi, who studied
neuronal precursor cells derived from embryonic stem cells … looking at subtler hints, such as …

Tales from the crypt: new insights into intestinal stem cells

H Gehart, H Clevers - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
cells, and together constitute the intestinal stem cell niche. Intestinal stem cells and early
progenitor cells … A first hint to answering this question comes from the field of epigenetics. …

History and perspective of stem cell research

A Bongso, M Richards - Best practice & research Clinical obstetrics & …, 2004 - Elsevier
… The earliest human embryonic stem cell (hESC) lines derived in our laboratory have been
… Several reports hint that MSCs can form a variety of cell types in the laboratory, including fat …

MicroRNAs: key regulators of stem cells

VK Gangaraju, H Lin - Nature reviews Molecular cell biology, 2009 - nature.com
… Depletion of maternal Dicer1 severely affects PGC formation in the early embryos 65 . In …
) of the planarian Schmidtea mediterranea 71 , which hints at a possibility that piRNAs might …

[HTML][HTML] Stem cells, cancer, and epigenetics

SB Baylin - StemBook [Internet], 2009 - ncbi.nlm.nih.gov
… These epigenetic abnormalities for pathways important to stem/progenitor cell control in
early … In terms of the key protein complexes, key hints are emerging which link lowering, by …

[HTML][HTML] Effect of Mother's Age and Pathology on Functional Behavior of Amniotic Mesenchymal Stromal CellsHints for Bone Regeneration

M Matteo, E Beccia, A Carbone, S Castellani, L Milillo… - Applied Sciences, 2019 - mdpi.com
… the cell types used for bone regenerative purposes, stem cellsstem cells (MSCs) have
been identified as a significant cell … The canonical Wnt signaling is involved in early osteoblast …

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective

C Brisken, S Duss - Stem cell reviews, 2007 - Springer
… of stem cells and their niches in the course of menstrual cycles may be an important early
and that we observe upregulation of Notch signaling in the culture as a late event hint at the …

Harnessing the power of stem cells

G Vogel - 1999 - science.org
… In fact, some hints from developmental biologists suggest that neuronal … changes “that
have only occurred in the complex context of the early embryo are now happening before your …