… -derived acetaldehyde and thereby protects tissues and cells from oxidative damage. Deficient
variant ALDH2*2 genotype is prevalent among East Asians … of toxic aldehydes, thereby …

… Combined with demographic history in East Asian, our results showed that the presence
of ALDH2⁎487Lys allele in peripheral regions of China might be the results of historical …

… loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2. Found
in approximately 560 million people of East Asian descent, ALDH2*2 reduces enzymatic …

… Coronary spastic angina (CSA) is a common disease among East Asians, including … of the
variant aldehyde dehydrogenase 2 (ALDH2*2) genotype is prevalent among East Asians. We …

… A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) … , variant and
ALDH2*2 for the common East Asian E504K mutant variant) we designated these new variants …

… acetaldehyde dehydrogenase activity of this variant. In the present study we compared the
wild type enzyme (ALDH2*1) with the Asian variant (… Alda-1 increased acetaldehyde oxidation …

… a variant allele of mitochondrial aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, commonly
occurs in East Asians … This unique allelic variation significantly influences drinking behavior …

… 25 Eckey, R.; Agarwal, DP; Saha, N.; Goedde, HW: Detection and partial characterization
of a variant form of cytosolic aldehyde dehydrogenase isozyme. Hum. Genet. …

… that studied East Asian populations to … variation and serum lipid and/or lipoprotein levels.
We found an association of ALDH2* 2 allele and low HDL-C concentration in East Asians. …

… Mitochondrial aldehyde dehydrogenase (ALDH2) is an enzyme detoxifying toxic aldehydes
… encoding deficient enzyme activity is prevalent in up to 40% among East Asians [8, 10]. …