Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis

H Sawada - Expert opinion on pharmacotherapy, 2017 - Taylor & Francis
… Pivotal study of edaravone to treat ALS Here, we review clinical trials using edaravone to
treat Amyotrophic lateral sclerosis (ALS) [Citation1–Citation3]. One was an open-label small-…

A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy?

PA Lapchak - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
… This study showed that edaravone treatment for 7 days could only produce a modest clinical
… Certainly with treatment durations of 6 – 14 days for the clinical efficacy studies assessed in …

Long-term efficacy of edaravone in patients with acute myocardial infarction

K Tsujita, H Shimomura, K Kaikita, H Kawano… - Circulation …, 2006 - jstage.jst.go.jp
… that the administration of edaravone just prior to … clinical outcomes in AMI patients have not
yet been clarified. The purpose of the present study was to clarify the efficacy of edaravone on …

Edaravone for the treatment of amyotrophic lateral sclerosis

H Yoshino - Expert Review of Neurotherapeutics, 2019 - Taylor & Francis
… pharmacological properties of edaravone and the progress of clinical trials conducted to
evaluate the efficacy of this drug in the treatment of ALS. Expert commentary: Edaravone is the …

A randomized controlled clinical trial to compare the safety and efficacy of edaravone in acute ischemic stroke

P Sharma, M Sinha, R Shukla, RK Garg… - Annals of Indian …, 2011 - journals.lww.com
… This study aims to evaluate the efficacy of edaravone in terms of functional … the efficacy of
edaravone outside Japan. The aim of this study was to investigate the effects of edaravone in …

Efficacy and safety of edaravone in treatment of amyotrophic lateral sclerosis—a systematic review and meta-analysis

L Luo, Z Song, X Li, n Huiwang, Y Zeng, n Qinwang… - Neurological …, 2019 - Springer
… of edaravone in the treatment of amyotrophic lateral sclerosis remain controversial. We
performed a meta-analysis to evaluate the efficacy and safety of edaravone in the treatment of …

Safety and efficacy of Edaravone Dexborneol versus edaravone for patients with acute ischaemic stroke: a phase II, multicentre, randomised, double-blind, multiple …

J Xu, Y Wang, A Wang, Z Gao, X Gao… - Stroke and Vascular …, 2019 - svn.bmj.com
… safety and efficacy of Edaravone Dexborneol compared with edaravone in treating patients
… Our result showed that, compared with edaravone alone, Edaravone Dexborneol was safe …

Safety and effectiveness of long-term intravenous administration of edaravone for treatment of patients with amyotrophic lateral sclerosis

S Witzel, A Maier, R Steinbach, J Grosskreutz… - JAMA …, 2022 - jamanetwork.com
… In summary, evidence for the efficacy of edaravone in the treatment of patients with ALS
is limited to short-term beneficial effects on disease progression observed in the MCI186-19 …

Safety and efficacy of edaravone in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

M Gao, L Zhu, J Chang, T Cao, L Song, C Wen… - Clinical Drug …, 2023 - Springer
… However, a recent study showed that intravenous edaravone may not provide any disease-…
clinical efficacy of edaravone and whether edaravone should be recommended for treating

Safety and efficacy of edaravone for patients with acute stroke: A protocol for randomized clinical trial

H Shan, G Jiao, X Cheng, Z Dou - Medicine, 2021 - journals.lww.com
Edaravone is an antioxidant and oxygen radical scavenger that can inhibit lipid peroxidation
… This is the first randomized controlled trial to assess the efficacy of edaravone for treating