Gap junction-dependent increases in smooth muscle cAMP underpin the EDHF phenomenon in rabbit arteries
HJ Taylor, AT Chaytor, DH Edwards… - … and biophysical research …, 2001 - Elsevier
… In the present study we have used rabbit artery and vascular bed preparations to test the …
encompass several characteristics of the “EDHF phenomenon” noted above. These include (i) …
encompass several characteristics of the “EDHF phenomenon” noted above. These include (i) …
Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses
C De Wit, TM Griffith - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
… In isolated rabbit arteries, EDHF-type relaxations are associated with NO- and prostanoid-independent
elevations in smooth muscle cAMP levels that peak ∼15-30 s after exposure to …
elevations in smooth muscle cAMP levels that peak ∼15-30 s after exposure to …
The alternative: EDHF
M Félétou, PM Vanhoutte - Journal of molecular and cellular cardiology, 1999 - Elsevier
… restricted to describe phenomena in which endoit disappears in K+ … in EDHFmediated
relaxation in cerebral arteries. Br J Pharmacol polarization of rabbit mesenteric arteries via ATP-…
relaxation in cerebral arteries. Br J Pharmacol polarization of rabbit mesenteric arteries via ATP-…
EDHF: spreading the influence of the endothelium
CJ Garland, CR Hiley, KA Dora - British journal of …, 2011 - Wiley Online Library
… So the EDHF phenomenon came to be recognized as smooth muscle relaxation in blood …
arteries used in this study were the rat hepatic and mesenteric arteries, and while the EDHF …
arteries used in this study were the rat hepatic and mesenteric arteries, and while the EDHF …
EDHF: bringing the concepts together
R Busse, G Edwards, M Félétou, I Fleming… - Trends in …, 2002 - cell.com
… EDHF phenomenon: (1) the increase in endothelial [Ca 2+ ] i triggers the synthesis of a
cytochrome P450 metabolite that is essential for the subsequent EDHF-… the EDHF phenomenon …
cytochrome P450 metabolite that is essential for the subsequent EDHF-… the EDHF phenomenon …
EDHF: new therapeutic targets?
M Félétou, PM Vanhoutte - Pharmacological research, 2004 - Elsevier
… This phenomenon is endothelium-dependent, but although nitric oxide is involved in some
… renal arteries of hypercholesterolemic rabbits an enhancement of the contribution of EDHF …
… renal arteries of hypercholesterolemic rabbits an enhancement of the contribution of EDHF …
Connexin‐mimetic peptides dissociate electrotonic EDHF‐type signalling via myoendothelial and smooth muscle gap junctions in the rabbit iliac artery
AT Chaytor, LM Bakker, DH Edwards… - British journal of …, 2005 - Wiley Online Library
… the EDHF phenomenon is electrotonic in nature, and highlight the contribution of myoendothelial
and homocellular smooth muscle communication via gap junctions to arterial function. …
and homocellular smooth muscle communication via gap junctions to arterial function. …
[PDF][PDF] Factors, fiction and endothelium-derived hyperpolarizing factor-EDH (F)
SL Sandow - Proceedings of the Australian Physiological and …, 2004 - aups.org.au
… for MEGJs in the action of K+ as EDHF.However, once a role for … diffusible EDHF may be
redundant, since the EDHF phenomenon … artery of the rabbit, apamin alone abolished the EDHF …
redundant, since the EDHF phenomenon … artery of the rabbit, apamin alone abolished the EDHF …
EDHF: an update
M Félétou, PM Vanhoutte - Clinical science, 2009 - portlandpress.com
… substances can be built in specific arteries and especially in those of the rabbit, most of
the … size of the artery [147], a phenomenon that parallels the contribution of the EDHF-mediated …
the … size of the artery [147], a phenomenon that parallels the contribution of the EDHF-mediated …
Factors, fiction and endothelium‐derived hyperpolarizing factor
SL Sandow - Clinical and Experimental Pharmacology and …, 2004 - Wiley Online Library
… as EDHF. However, once a role for MEGJ is included in this mechanism, a role for K + as a
diffusible EDHF may be redundant, because the EDHF phenomenon … In the rabbit iliac artery, …
diffusible EDHF may be redundant, because the EDHF phenomenon … In the rabbit iliac artery, …
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