Effect of acidosis, oxidative stress, and glutamate toxicity on the survival of mature and immature cultured cerebellar granule cells
EV Stelmashuk, EA Belyaeva, NK Isaev - Neurochemical Journal, 2007 - Springer
… These factors included acidosis, oxidative stress, and glutamate toxicity. Incubation of both
… ) cerebellar granule cells for 24 hours under the conditions of external acidosis or oxidative …
… ) cerebellar granule cells for 24 hours under the conditions of external acidosis or oxidative …
Hydrogen peroxide induced chemokine production in the glia-rich cultured cerebellar granule cells under acidosis
I Miura, K Miyamoto, K Nakamura, Y Watanabe - Life sciences, 2002 - Elsevier
… cultured rat cerebellar granule cells under acidified conditions. … detected under acidosis in
astrocyte-rich cultured cell. Upon … Effect of acidosis on hydrogen peroxide injury to the isolated …
astrocyte-rich cultured cell. Upon … Effect of acidosis on hydrogen peroxide injury to the isolated …
Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: an in vitro model for the study of cell death mechanisms in Wernicke's …
P Pannunzio, AS Hazell, M Pannunzio… - Journal of …, 2000 - Wiley Online Library
… changes, primary cultures of rat cerebellar granule cells were exposed to thiamine-deficient …
to study the effects of TD on neuronal cell metabolism and survival. Treatment of these …
to study the effects of TD on neuronal cell metabolism and survival. Treatment of these …
Extracellular presence of IL-8 in the astrocyte-rich cultured cerebellar granule cells under acidosis
Y Watanabe, I Miura, Y Ohgami, M Fujiwara - Life sciences, 1998 - Elsevier
… of brain function, we examined the effects of acidosis on the production of IL-8 in cultured
neurons and/or astrocyte-rich cerebellar granule cells as assessed by the ELISA method. A …
neurons and/or astrocyte-rich cerebellar granule cells as assessed by the ELISA method. A …
… acidosis specifically reduces functional expression of N-methyl-D-aspartate receptors and increases long-term survival in primary cultures of cerebellar granule cells
JC Leahy, Q Chen, ML Vallano - Neuroscience, 1994 - Elsevier
… expression in granule cell cultures is … in granule cells, in effect producing a functional level
of expression more comparable to that observed in vivo. To test this, cerebellar granule cells …
of expression more comparable to that observed in vivo. To test this, cerebellar granule cells …
Acidosis-induced zinc-dependent death of cultured cerebellar granule neurons
NK Isaev, EV Stelmashook, SV Lukin, D Freyer… - Cellular and molecular …, 2010 - Springer
… We examined the effect of external acidosis on the survival of cultured cerebellar granule …
in the nutrient medium to 6.5 or 6.0 induced cell death. Quantitative analysis of fixed cultures …
in the nutrient medium to 6.5 or 6.0 induced cell death. Quantitative analysis of fixed cultures …
The impact of extracellular acidosis on dendritic cell function
ME Vermeulen, R Gamberale… - Critical Reviews™ in …, 2004 - dl.begellhouse.com
… aimed to analyze the effect of extracellular pH on immune cells. In this review, we focus
on the influence of extracellular acidosis on the function of immature dendritic cells (DCs). …
on the influence of extracellular acidosis on the function of immature dendritic cells (DCs). …
Arachidonic acid‐induced H+ and Ca2+ increases in both the cytoplasm and nucleoplasm of rat cerebellar granule cells
WH Chen, CR Chen, KT Yang… - The Journal of …, 2001 - Wiley Online Library
… al. 1999) in granule cells. If such an effect occurred in our system, the acidosis evoked by AA
… load) to test directly the effect of AA metabolites on the acidosis, our results suggest that the …
… load) to test directly the effect of AA metabolites on the acidosis, our results suggest that the …
Cellular acidosis inhibits assembly, disassembly, and motility of stress granules
EM Chudinova, ES Nadezhdina, PA Ivanov - Biochemistry (Moscow), 2012 - Springer
… We studied the effect of pH of the culture medium on the dynamics of SG disassembly in
the presence of cyclo heximide. Cycloheximide was added to the arsenite con taining culture …
the presence of cyclo heximide. Cycloheximide was added to the arsenite con taining culture …
Unravelling the interplay between extracellular acidosis and immune cells
F Erra Díaz, E Dantas, J Geffner - Mediators of inflammation, 2018 - Wiley Online Library
… by inhibiting the Na + /H + antiporter, we hypothesized that the prosurvival effect induced by
… ), it was shown that the release of perforin/granzyme-containing granules, the secretion of …
… ), it was shown that the release of perforin/granzyme-containing granules, the secretion of …
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