… The determination of receptor types involved in the effects of tachykinins in the airways has
been done with synthetic agonists and antagonists binding specifically to NK-1, NK-2 and NK-…

… inflammation and to exitive C-fibre afferents in airways and lead to a local … release of
tachykinins which are responsible for several biological effects in the bronchopulmonary system: …

… expressed by target cells in the airways, mimic several of the … on the comparison of altered
airway function in vehicle- versus … Occurrence and effects of multiple tachykinins, substance P, …

… the main barrier against tachykinins released within or in … of the airway epithelium, inhibitors
of NEP still potentiate the bronchomotor effects of endogenous and exogenous tachykinins [9…

… To our knowledge, no studies have been reported on the effect of tachykinins on isolated
asthmatic bronchi. It has been demonstrated for adenosine that such an approach could reveal …

… Conversely, steroid treatment might produce its favorable effect on airway function by
reducing neurogenic inflammation, in part through its ability to increase NEP expression in the …

… The airway effects of the tachykinins are largely mediated by tachykinin NK 1 and NK 2 …
In view of their potent effects on the airways, tachykinins have been put forward as possible …

… effect of tachykinin NK2 receptor antagonists has clearly been demonstrated in several
experimental conditions, but the effect of tachykinin NK1 receptor antagonists is still debated. …

… airways so that tachykinin have a greater effect because of slower degradation. The distribution
of NEP in airways of … do not suggest a reduced enzyme effect in more peripheral airways. …

… of tachykinin receptor antagonists for use in airways diseases … The relative importance of
the three tachykinin receptors as … most of the effects of tachykinins in the airways are mediated …