… oral anticoagulants, a growing body of evidence from indirect comparisons and observational
studies is suggesting that each direct oral anticoagulant … effectiveness and safety research …

… K antagonist oral anticoagulants (… on oral anticoagulants (OACs) are 75 years or older, and
approximately half of these are women.7 No RCT has investigated the efficacy and safety of …

… different direct oral anticoagulants (DOACs). Thus, we systematically reviewed and meta-analyzed
observational studies assessing the comparative effectiveness and safety of DOACs …

Background and Objective Atrial fibrillation (AF), the most common cardiac arrhythmia,
typically increases with age. Oral anticoagulants (OACs) are the cornerstone of treatment to …

… Direct oral anticoagulants are contraindicated in patients with … the pharmacology of direct
oral anticoagulants, summarise the … perspectives for the development of oral anticoagulants. …

We compared the effectiveness and safety of direct oral anticoagulants (DOAC) vs patient
self-managed warfarin therapy (PSM) in patients with atrial fibrillation. We linked prospectively …

… effectiveness and safety results between NOACs and warfarin with previous studies. For
example, this analysis had more statistical power in evaluating less frequent events (eg, …

Purpose The findings from the observational studies comparing the effectiveness and safety
of non–vitamin K antagonist oral anticoagulants (NOACs) versus vitamin K antagonists (…

Background: Since the direct oral anticoagulants (DOAC) were introduced, oral anticoagulant
(OAC) prescription patterns have rapidly changed in patients with atrial fibrillation (AF). We …

Introduction Data from clinical trials indicate that direct oral anticoagulants (DOACs) are
noninferior and safer than conventional therapy (low-molecular-weight heparin followed by a …