… , thus promoting effector cell differentiation at the expense of memory cell formation. , 51 …
of effector T cells. Interestingly, effector CD8 + T cells generated in the absence of CD4 + T …

During an infection, T cells can differentiate into multiple types of effector and memory T cells,
which help to mediate pathogen clearance and provide long-term protective immunity. …

… of effector and memory CD8 + T-cell differentiation at the single cell level. These studies
have begun to uncover the diversity of form and function within effector and memory T-cell …

… process of Th17 cells [9••, 10••] and Th2 cells [11 • ]. Th17 cell differentiation is regulated
by … changes that in turn regulate effector CD4 T cell differentiation and function. So how …

… Here we will focus on how these changes may influence memory-cell differentiation. Naive
T cells are presumed to require basal levels of energy to support their survival, which are …

… naïve B cell can produce all of these different cell fates remains … B cells produced only one
type of effector cell subset, whereas others produced all subsets. The capacity to differentiate …

… affinity drove responding T cells into asymmetric cell division. The ensuing … and differentiated
into short-lived effector cells expressing the integrin VLA-4, allowing the activated T cell to …

… for the pathway of differentiation from naïve to memory that suggests that Tem are not fully
differentiated effector cells, but derived from central memory T cells as originally suggested by …

… has been washed free of effector cells and nonviable target cells. This assay therefore … ) of
target cells, in contrast to the Takasugi and Klein assay (21) which is influenced by target cell …

… However, the effector/memory differentiation … similar effector CD8 + T cell differentiation
remains an open question. In this study we demonstrate that effector CD8 + T cell differentiation …