… Moreover, when we transferred in vitro–primed day-7 effector cells, CXCR3 −/− OT-I cells
now contracted at the same rate as WT OT-I cells in vivo (Fig. 5, H and I). Collectively, these …

… effector/memory T cells (Tem), defined as CD45RO+ and FAS+ CD4+ T cells and decreased
CD31+ and α4β7+ CD4+ T cells … T cells (Treg) from PD patients to suppress effector T cell …

… Although these studies showed that memory cells are derived from effector cells, not every
effector cell maintains the same potential to become memory cell over the course of infection. …

… ) revealing proliferating cells among the injected effector T cells (blue and … effector cells
after migration into the LP and into the T-cell area of mLN demonstrates that mLN effector T cells …

… c | The transcriptional programmes that control terminal effector cell differentiation and
memory cell potential seem to be based on the graded expression or activity of certain competing …

… Herein, we review the roles of T cell subsets on neuronal degeneration and regeneration
(… remains elusive, largely because the targeted effector cells are unknown. Additionally, it …

… In summary, we conclude that CD8 + T cells drive axonal degeneration in the aged CNS.
The effector … Thus, CD8 + CNS-associated T cells are important effectors of aging-related …

… to stimulate effector T cell expansion and differentiation 1,2,3,4,5 . We hypothesized that
vaccines designed to maintain differentiated effector memory T cell (T EM cell) responses 5,6 at …

… − CCR7 − effector memory lymphocytes. We provide evidence that effector memory CD8 +
T … across human BBB-endothelial cells than non-effector memory cells. We further show that …

… deliver peak effector responses only after T CM cells have … As T-cell effector responses are
likely to be much more … able to ‘pre-position’ differentiated effector cells (T EM ) at such early …