[HTML][HTML] Context-dependent effects of cellular senescence in cancer development
P Lecot, F Alimirah, PY Desprez, J Campisi… - British journal of …, 2016 - nature.com
… roles of senescent cells, highlighting conditions under which the senescence response does
… By better understanding the context-dependent effects of cellular senescence, it may be …
… By better understanding the context-dependent effects of cellular senescence, it may be …
[HTML][HTML] Mechanisms and functions of cellular senescence
N Herranz, J Gil - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
… factors termed the senescence-associated secretory … cellular senescence with a special
focus on their translational relevance and suitability for identifying and characterizing senescent …
focus on their translational relevance and suitability for identifying and characterizing senescent …
On the evolution of cellular senescence
… and detrimental effects is broken, if possible. That means if the negative effects that emerge
… ) from the positive, anti-tumorigenic effects of cellular senescence, then we would expect to …
… ) from the positive, anti-tumorigenic effects of cellular senescence, then we would expect to …
[HTML][HTML] Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
MC Velarde, R Menon - Journal of Endocrinology, 2016 - joe.bioscientifica.com
… effects of cellular senescence on female reproductive aging and pregnancy. We discuss how
senescent … We also describe how cellular senescence plays an important role in placental …
senescent … We also describe how cellular senescence plays an important role in placental …
Cellular senescence: the sought or the unwanted?
Y Sun, JP Coppé, EWF Lam - Trends in Molecular Medicine, 2018 - cell.com
… to tackle senescent cells are in development pipelines to counter the adverse effects of
cellular senescence in the clinic. We focus on recent discoveries in senescence research and …
cellular senescence in the clinic. We focus on recent discoveries in senescence research and …
Cellular senescence: from physiology to pathology
D Muñoz-Espín, M Serrano - Nature reviews Molecular cell biology, 2014 - nature.com
… our view of cellular senescence as a … , senescent cells arrest their own proliferation, recruit
phagocytic immune cells and promote tissue renewal. This sequence of events — senescence…
phagocytic immune cells and promote tissue renewal. This sequence of events — senescence…
Effect of cellular senescence on the growth of HER2-positive breast cancers
MF Zacarias-Fluck, B Morancho… - Journal of the …, 2015 - academic.oup.com
… However, cellular senescence has not been characterized in HER2-positive tumors. … effect
of lower, pathophysiologically relevant levels of HER2 signaling on the onset of senescence. …
of lower, pathophysiologically relevant levels of HER2 signaling on the onset of senescence. …
[HTML][HTML] Cellular senescence: the good, the bad and the unknown
W Huang, LTJ Hickson, A Eirin, JL Kirkland… - Nature Reviews …, 2022 - nature.com
… of senescence, whereas p16 maintains cellular senescence … Interest in cellular senescence
and in senescence-… addition to driving ageing, cellular senescence has important roles in the …
and in senescence-… addition to driving ageing, cellular senescence has important roles in the …
Lamin B1 fluctuations have differential effects on cellular proliferation and senescence
O Dreesen, A Chojnowski, PF Ong, TY Zhao… - Journal of Cell …, 2013 - rupress.org
… is a cause or a consequence of senescence, LMNB1 was … senescence. In contrast, LMNB1
overexpression impairs proliferation and culminates in cellular senescence, with these effects …
overexpression impairs proliferation and culminates in cellular senescence, with these effects …
The role of cellular senescence in cardiac disease: basic biology and clinical relevance
M Mehdizadeh, M Aguilar, E Thorin… - Nature Reviews …, 2022 - nature.com
… The involvement of cellular senescence in other important entities, such as cardiac … biology
of cellular senescence and discuss what is known about the role of cellular senescence and …
of cellular senescence and discuss what is known about the role of cellular senescence and …