Effects of frailty in survival analysis

OO Aalen - Statistical methods in medical research, 1994 - journals.sagepub.com
… , also called frailty, is a major concern in the application of survival analysis. Hazard rates do
… , but are strongly influenced by selection effects operating in the population. The individuals …

Effect of frailty on marginal regression estimates in survival analysis

R Henderson, P Oman - Journal of the Royal Statistical Society …, 1999 - academic.oup.com
survival data and association in multivariate survival can both be modelled by the inclusion
of frailty effects… This paper investigates the consequences of ignoring frailty in analysis, fitting …

Frailty models for survival data

P Hougaard - Lifetime data analysis, 1995 - Springer
… A frailty model is a random effects model for time variables, where the random effect (the
frailty) has a multiplicative effect on … times given the frailty. This approach can be used both for …

Survival of elderly outpatients: effects of frailty, multimorbidity and disability

DEC Leme, RP Thomaz, FSA Borim… - Ciência & Saúde …, 2019 - SciELO Public Health
… This study aims to analyze the impact of frailty, multimorbidity and disability on the survival
of … It is a longitudinal study, with 133 elderly people initially evaluated in relation to frailty, …

A tutorial on frailty models

TA Balan, H Putter - Statistical methods in medical research, 2020 - journals.sagepub.com
… We concentrate on the use of frailty models in survival analysis. … In section 3, we analyze
the effect of unobserved heterogeneity in shared frailty models, covering clustered survival data, …

ML and REML estimation in survival analysis with time dependent correlated frailty

KKW Yau, CA McGilchrist - Statistics in Medicine, 1998 - Wiley Online Library
… The frailty model for subject effects is better, but can be … In our analysis, the frailty correlation
parameter is estimated to … REML, indicating that there is possibly a serial correlation effect

[PDF][PDF] Frailty models

A Wienke - Rostock, Germany Max Planck institute for …, 2003 - ressources-actuarielles.net
… Normally, in most clinical applications, survival analysisfrailty model is a random effect
model for time-to-event data, where the random effect (the frailty) has a multiplicative effect

Multivariate survival analysis using piecewise gamma frailty

MC Paik, WY Tsai, R Ottman - Biometrics, 1994 - JSTOR
… In this note we propose a frailty model called piecewise gamma frailty for correlated survival
data with random effects having a nested structure. In frailty models, a dependence function …

Survival analysis of under-five mortality using Cox and frailty models in Ethiopia

DG Ayele, TT Zewotir, H Mwambi - Journal of Health, Population and …, 2017 - Springer
effects and the variance of frailty (cluster/probability sampling unit (PSU)). As can be seen
from the table, the frailty … Therefore, this result shows that there are factors that have an effect

A general framework for random effects survival analysis in the Cox proportional hazards setting

DJ Sargent - Biometrics, 1998 - JSTOR
… Previously, random effects models for survival data have … we develop a method of random
effect analysis of survival data, the … In the model with only a single frailty random effect term, we …