Effects of melatonin on the nitric oxide system and protein nitration in the hypobaric hypoxic rat hippocampus

CC Huang, CJ Lai, MH Tsai, YC Wu, KT Chen… - BMC neuroscience, 2015 - Springer
… , the potential effects of melatonin on nitric oxide system and protein nitration following …
We also sought to elucidate whether melatonin treatment would have any beneficial effects

Protein nitration increased by simulated weightlessness and decreased by melatonin and quercetin in PC12 cells

L Qu, T Yang, Y Yuan, P Zhong, Y Li - Nitric Oxide, 2006 - Elsevier
effects of reactive nitrogen species on protein nitration in PC12 cells during clinorotation. The
effects of melatonin and quercetin on protein nitration … role of melatonin or quercetin as an …

Melatonin, its metabolites and their interference with reactive nitrogen compounds

R Hardeland - Molecules, 2021 - mdpi.com
melatonin nitration by peroxynitrite remained rather modest. One study reported the absence
of stable nitration … Moreover, the appearance of nitrated proteins can be regarded as a sign …

Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin

R Tao, JY Huang, X Shao, W Ye, Y Tian… - Journal of Pineal …, 2013 - Wiley Online Library
… direct evidence for protein nitration, we used purified Keap1 protein subjected to in vitro
protein nitration with ONOO − as a model for the identification of possible nitrated sites. Silver …

Melatonin and its metabolites as anti-nitrosating and anti-nitrating agents

R Hardeland - 2011 - publications.goettingen-research …
protein thiols in ETC complexes [9, 14, 15, 58, 59]. In summary, all these effects by RNS and
… irons, S-nitrosation, nitration and oxidation of respirasomal proteins, as well as peroxidation …

Melatonin and nitric oxide

S Aydogan, MB Yerer, A Goktas - Journal of endocrinological investigation, 2006 - Springer
… that melatonin protects lipids in membranes, proteins in the cytosol, and DNA in the nucleus
and mitochondria from free radical damage. Melatonin … scavenging effects of melatonin are …

Effect of melatonin on the generation of nitric oxide in murine macrophages

S Zhang, W Li, Q Gao, T Wei - European journal of pharmacology, 2004 - Elsevier
nitration by melatonin plays an important role in the regulation of NF-κB. Upon
lipopolysaccharide/interferon-γ exposure, there was rapid tyrosine nitration of … pathway by protein

Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis …

C Wang, MM Ahmed, Q Jiang, N Lu… - Journal of pineal …, 2017 - Wiley Online Library
… how melatonin functions in the preservation of tight junctions by reducing protein nitration
of … We provide detailed molecular mechanisms for the protective effect of melatonin on brain …

… the protective effect of melatonin against methotrexate-induced small intestinal damage: effect mediated by attenuation of nitrosative stress, protein tyrosine nitration …

VK Kolli, I Kanakasabapathy, M Faith… - Cancer chemotherapy …, 2013 - Springer
… in nitrate levels and protein tyrosine nitration in the various … Melatonin is an endogenously
produced, multifunctioning … , are molecular targets for melatonin and its metabolites [18]. …

Melatonin and the electron transport chain

R Hardeland - Cellular and Molecular Life Sciences, 2017 - Springer
protein nitrosation, nitration and oxidation, changes that lead to electron overflow or even
backflow and, thus, increased formation of superoxide anions (O 2 · − ). Melatonin … of melatonin