Effects of minocycline on hind-limb motor function and gray and white matter injury after spinal cord ischemia in rats

M Takeda, M Kawaguchi, T Kumatoriya, T Horiuchi… - Spine, 2011 - journals.lww.com
effects of minocycline on spinal cord ischemicischemia and in patients with stroke. In 1998,
Yrjänheikki et al 13 reported that, in a gerbil model of global cerebral ischemia, minocycline

[HTML][HTML] Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review

Y Naderi, Y Panahi, GE Barreto… - Neural regeneration …, 2020 - journals.lww.com
… concerning the protective effects of minocycline in focal cerebral ischemia in animal models
effects of minocycline in ischemic stroke. These studies revealed that minocycline increases …

[HTML][HTML] Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury

RB Shultz, Y Zhong - Neural regeneration research, 2017 - journals.lww.com
Minocycline hydrochloride (MH), a semi-synthetic tetracycline derivative, is a clinically available
antibiotic and anti-inflammatory drug that also exhibits potent neuroprotective activities. …

Minocycline effectively protects the rabbit's spinal cord from aortic occlusion-related ischemia

B Drenger, Y Fellig, D Ben-David, B Mintz… - … of Cardiothoracic and …, 2016 - Elsevier
minocycline administration after ischemia was 50% smaller than the pre-ischemia group,
indicating that minocycline … the destructive cascade to the spinal cord. Despite that neurons in …

Preservation of motor function after spinal cord ischemia and reperfusion injury through microglial inhibition

PD Smith, MT Bell, F Puskas, X Meng… - The Annals of thoracic …, 2013 - Elsevier
… inhibit microglial activation by administration of minocycline. Microglia activation (measured …
downstream effects of this inhibition. Ultimately, we hypothesized that minocycline

Evaluation of the neuroprotective effect of minocycline in a rabbit spinal cord ischemia model

K Watanabe, M Kawaguchi, K Kitagawa, S Inoue… - Journal of cardiothoracic …, 2012 - Elsevier
… spinal cord tissue. Third, a group in which minocycline was administered before ischemia
it is unclear whether the administration of minocycline before ischemia would be more effective …

Therapeutic effects of minocycline pretreatment in the locomotor and sensory complications of spinal cord injury in an animal model

K Afshary, M Chamanara, B Talari, P Rezaei… - Journal of Molecular …, 2020 - Springer
… Intraoperative cord compression and ischemia are … to evaluate the therapeutic effects of
minocycline, a promising … , a minocycline-treated group, and a minocycline pretreated group. …

Protective effects of minocycline on experimental spinal cord injury in rats

M Aras, M Altas, S Motor, R Dokuyucu, A Yilmaz… - Injury, 2015 - Elsevier
… The effects of minocycline on neuronal injury after spinal cord injury (SCI) are limited and
controversial. Therefore we aimed to investigate the protective effects of minocycline on tissue …

[HTML][HTML] Effect of minocycline on cerebral ischemia-reperfusion injury★

Y Zheng, L Xu, J Yin, Z Zhong, H Fan… - Neural regeneration …, 2013 - journals.lww.com
… the protective effects of minocycline on neuronal injuries induced by focal ischemia-reperfusion.
This study aimed to observe the effect of minocycline in rats following focal ischemia-…

Minocycline before aortic occlusion reduces hindlimb motor impairment, attenuates spinal cord damage and spinal astrocytosis, and preserve neuronal …

B Drenger, TJJ Blanck, B Piskoun, E Jaffrey… - … of Cardiothoracic and …, 2019 - Elsevier
cord ischemia in the rat was used for this study to determine whether a single, high-dose (10
mg/kg) of minocycline … during ischemia. Thirty minutes before thoracic aorta occlusion, …