Minocycline treatment in acute stroke: an open-label, evaluator-blinded study

Y Lampl, M Boaz, R Gilad, M Lorberboym, R Dabby… - Neurology, 2007 - AAN Enterprises
… These decisions were based on the fact that the minocycline effect on ischemic brain tissue
is at least partially dependent upon the inhibition mechanisms of the apoptotic pathway. In …

Minocycline development for acute ischemic stroke

SC Fagan, LE Cronic, DC Hess - Translational stroke research, 2011 - Springer
… Dose-finding studies in a rat model of focal cerebral ischemia suggested that minocycline’s
neuroprotective effect increased at doses higher than the usual antimicrobial dose (3 mg/kg) […

Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat

K Saganová, J Orendáčová, D Čížková, I Vanický - Neuroscience letters, 2008 - Elsevier
… Spinal cord white/gray matter Minocycline is widely used for its neuroprotective effects in
animal models of central nervous system injury and several neurodegenerative diseases. …

Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia

Z Liu, Y Fan, SJ Won, M Neumann, D Hu, L Zhou… - Stroke, 2007 - Am Heart Assoc
… the effect of minocycline on neurogenesis and functional recovery after cerebral focal ischemia.
… In addition to its acute neuroprotective effect in reducing ischemic core, we found that …

Minocycline and doxycycline: more than antibiotics

S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
Minocyclineischemia/reperfusion indicating attenuation of renal dysfunction and injury,
and reduced histological evidence of renal damage caused by ischemia/reperfusion Minocycline

Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats

M Ahmad, A Zakaria, KM Almutairi - Pharmacology Biochemistry and …, 2016 - Elsevier
… The present study aimed to investigate the neuroprotective effects of minocycline and
FK506 (Tacrolimus) individually and in combination on recovery from experimental spinal cord

Antibiotics with therapeutic effects on spinal cord injury: a review

K Afshari, N Momeni Roudsari… - Fundamental & …, 2021 - Wiley Online Library
… Sprague-Dawley rats Spinal cord ischemia by clamping the abdominal aorta FK506 (0.5
mg/… underlying the neuroprotective effects of minocycline on SCI as we will discuss below. …

[HTML][HTML] Inhibition of microglial activation by minocycline reduced preoligodendrocyte injury in a neonatal rat brain slice model

J Huang, G Liu, B Shi, G Shi, X He, Z Lu… - The Journal of Thoracic …, 2018 - Elsevier
… tetracycline, minocycline has been shown to provide protection against ischemic brain injury
… and provide further evidence that minocycline exerts protective effects through inhibition of …

Treatment efficacy with bone marrow derived mesenchymal stem cells and minocycline in rats after cerebral ischemic injury

S Bilen, F Pinarli, F Ak, E Fadillioglu, A Albayrak… - Stem Cell Reviews and …, 2013 - Springer
minocycline had a positive effecteffects of bone marrow derived MSCs, minocycline, and
combined therapy of these two on functional and histological improvement in cerebral ischemic

Inhibiting effect of minocycline on the regeneration of peripheral nerves

G Keilhoff, K Langnaese, G Wolf… - Developmental …, 2007 - Wiley Online Library
… Since there are no published results concerning Schwann cells as possible targets for
minocycline effects, we tested the action of minocycline on nonstimulated and LPS/IFNc-…