Minocycline treatment in acute stroke: an open-label, evaluator-blinded study
Y Lampl, M Boaz, R Gilad, M Lorberboym, R Dabby… - Neurology, 2007 - AAN Enterprises
… These decisions were based on the fact that the minocycline effect on ischemic brain tissue
is at least partially dependent upon the inhibition mechanisms of the apoptotic pathway. In …
is at least partially dependent upon the inhibition mechanisms of the apoptotic pathway. In …
Minocycline development for acute ischemic stroke
SC Fagan, LE Cronic, DC Hess - Translational stroke research, 2011 - Springer
… Dose-finding studies in a rat model of focal cerebral ischemia suggested that minocycline’s
neuroprotective effect increased at doses higher than the usual antimicrobial dose (3 mg/kg) […
neuroprotective effect increased at doses higher than the usual antimicrobial dose (3 mg/kg) […
Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat
K Saganová, J Orendáčová, D Čížková, I Vanický - Neuroscience letters, 2008 - Elsevier
… Spinal cord white/gray matter Minocycline is widely used for its neuroprotective effects in
animal models of central nervous system injury and several neurodegenerative diseases. …
animal models of central nervous system injury and several neurodegenerative diseases. …
Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia
Z Liu, Y Fan, SJ Won, M Neumann, D Hu, L Zhou… - Stroke, 2007 - Am Heart Assoc
… the effect of minocycline on neurogenesis and functional recovery after cerebral focal ischemia.
… In addition to its acute neuroprotective effect in reducing ischemic core, we found that …
… In addition to its acute neuroprotective effect in reducing ischemic core, we found that …
Minocycline and doxycycline: more than antibiotics
S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
… Minocycline … ischemia/reperfusion indicating attenuation of renal dysfunction and injury,
and reduced histological evidence of renal damage caused by ischemia/reperfusion Minocycline …
and reduced histological evidence of renal damage caused by ischemia/reperfusion Minocycline …
Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats
M Ahmad, A Zakaria, KM Almutairi - Pharmacology Biochemistry and …, 2016 - Elsevier
… The present study aimed to investigate the neuroprotective effects of minocycline and
FK506 (Tacrolimus) individually and in combination on recovery from experimental spinal cord …
FK506 (Tacrolimus) individually and in combination on recovery from experimental spinal cord …
Antibiotics with therapeutic effects on spinal cord injury: a review
K Afshari, N Momeni Roudsari… - Fundamental & …, 2021 - Wiley Online Library
… Sprague-Dawley rats Spinal cord ischemia by clamping the abdominal aorta FK506 (0.5
mg/… underlying the neuroprotective effects of minocycline on SCI as we will discuss below. …
mg/… underlying the neuroprotective effects of minocycline on SCI as we will discuss below. …
[HTML][HTML] Inhibition of microglial activation by minocycline reduced preoligodendrocyte injury in a neonatal rat brain slice model
J Huang, G Liu, B Shi, G Shi, X He, Z Lu… - The Journal of Thoracic …, 2018 - Elsevier
… tetracycline, minocycline has been shown to provide protection against ischemic brain injury
… and provide further evidence that minocycline exerts protective effects through inhibition of …
… and provide further evidence that minocycline exerts protective effects through inhibition of …
Treatment efficacy with bone marrow derived mesenchymal stem cells and minocycline in rats after cerebral ischemic injury
… minocycline had a positive effect … effects of bone marrow derived MSCs, minocycline, and
combined therapy of these two on functional and histological improvement in cerebral ischemic …
combined therapy of these two on functional and histological improvement in cerebral ischemic …
Inhibiting effect of minocycline on the regeneration of peripheral nerves
G Keilhoff, K Langnaese, G Wolf… - Developmental …, 2007 - Wiley Online Library
… Since there are no published results concerning Schwann cells as possible targets for
minocycline effects, we tested the action of minocycline on nonstimulated and LPS/IFNc-…
minocycline effects, we tested the action of minocycline on nonstimulated and LPS/IFNc-…