Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord …

L Sencar, DM Yilmaz, A Tuli, S Polat - Ultrastructural Pathology, 2020 - Taylor & Francis
… their effects on SCI. In this study, we aimed to evaluate effects of MP+minocycline combined
… in other nervous system diseases such as ischemia, Huntington’s disease and amyotrophic …

[HTML][HTML] Minocycline enhance the restorative ability of olfactory ensheathing cells by the upregulation of BDNF and GDNF expression after spinal cord injury

S Pourkhodadad, S Oryan, MM Hadipour… - Basic and Clinical …, 2021 - ncbi.nlm.nih.gov
… This study examined the effect of combined treatment with minocycline and olfactory …
after spinal cord injury model in rat. The results showed that injection of minocycline before …

Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

L Xu, SC Fagan, JL Waller, D Edwards, CV Borlongan… - BMC neurology, 2004 - Springer
… in acute neurological disorders such as ischemic stroke, intracerebral hemorrhage, spinal
cord injury, and traumatic brain injury. In this study, IV minocycline at doses that likely are safe …

Effects of minocycline on parameters of cardiovascular recovery after cardioplegic arrest in a rabbit Langendorff heart model

A Salameh, M Halling, T Seidel… - Clinical and …, 2015 - Wiley Online Library
… While the neuro-protective effects of minocycline in ischemia/reperfusion injury of brain
and spinal cord are established, its potential role in cardiac protection during an ischemia/…

Minocycline ameliorates depressive-like behavior and demyelination induced by transient global cerebral ischemia by inhibiting microglial activation

B Du, H Li, H Zheng, C Fan, M Liang, Y Lian… - Frontiers in …, 2019 - frontiersin.org
… by minocycline treatment after GCI. Collectively, our data demonstrated that minocycline
exerts an anti-depressant effect by … We tested the effects of minocycline on monoaminergic …

The potential of minocycline for neuroprotection in human neurologic disease

D Zemke, A Majid - Clinical neuropharmacology, 2004 - journals.lww.com
… Of particular interest is the ability of minocycline to diffuse … , minocycline has been found
to have beneficial effects on … of hypoxia-ischemia, it was found that minocycline prevented …

Minocycline and intracerebral hemorrhage: influence of injury severity and delay to treatment

A Szymanska, J Biernaskie, D Laidley… - Experimental …, 2006 - Elsevier
Minocycline (MC), a commonly used antibiotic that also has … The objective of this study was
to examine the effects of MC on … Minocycline given for either 5 or 14 days also provided no …

Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke

N Matsukawa, T Yasuhara, K Hara, L Xu, M Maki… - BMC neuroscience, 2009 - Springer
… that minocycline in the periphery affords protective effects on kidney cells against ischemia
via … We report here that minocycline also promoted protection against ischemia in the CNS by …

Minocycline attenuates ethanol-induced cell death and microglial activation in the developing spinal cord

Z Ren, X Wang, M Xu, JA Frank, J Luo - Alcohol, 2019 - Elsevier
… whether minocycline could protect spinal cord neurons against ethanol-induced damage. In
this study, we showed that minocycline … cytokines in the developing spinal cord. Moreover, …

Impact of minocycline on neurodegenerative diseases in rodents: a meta-analysis

C Li, K Yuan, H Schluesener - Reviews in the Neurosciences, 2013 - degruyter.com
… ) of minocycline was most effective. In conclusion, minocycline exerts neuroprotective effects
in … of this effect. However, there is insufficient information from these animal models on side …