Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia

T Roth, D Seiden, S Sainati, S Wang-Weigand, J Zhang… - Sleep medicine, 2006 - Elsevier
… patients with chronic insomnia reported reductions in sleep latency and increases in total
sleep time during a 5-week nightly treatment with ramelteon. Compared to baseline, ramelteon

Ramelteon in the treatment of chronic insomnia: systematic review and meta‐analysis

J Liu, L Wang - International journal of clinical practice, 2012 - Wiley Online Library
… Although no differences of next-day residual effects were found between placebo and any
ramelteon dose group in our work. However, the recent study based on the healthy population …

Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia

G Zammit, M Erman, S Wang-Weigand… - Journal of Clinical …, 2007 - jcsm.aasm.org
… and withdrawal effects following discontinuation of the 5-week ramelteon treatment. These …
with chronic insomnia, in which ramelteon showed no rebound insomnia or withdrawal effects

Long-term safety and efficacy of ramelteon in Japanese patients with chronic insomnia

M Uchiyama, M Hamamura, T Kuwano, H Nagata… - Sleep Medicine, 2011 - Elsevier
… tolerated without residual effects, withdrawal symptoms or rebound insomnia in the longer
… safety of long-term administration of ramelteon in Japanese patients with chronic insomnia. …

An efficacy, safety, and dose–response study of ramelteon in patients with chronic primary insomnia

M Erman, D Seiden, G Zammit, S Sainati, J Zhang - Sleep medicine, 2006 - Elsevier
… dose–response of ramelteon in patients with chronic primary insomnia. Because cognitive
… agent, this study also assessed the effects of ramelteon in the patient groups by using visual …

Effect of ramelteon on middle-of-the-night balance in older adults with chronic insomnia

G Zammit, S Wang-Weigand, M Rosenthal… - Journal of Clinical …, 2009 - jcsm.aasm.org
… The current study evaluated the effects of ramelteon and placebo on balance, mobility, and
memory impairment after middle-of-the-night awakening in older adults with chronic insomnia

Ramelteon for the treatment of insomnia in adults: a systematic review and meta-analysis

A Kuriyama, M Honda, Y Hayashino - Sleep medicine, 2014 - Elsevier
… the efficacy of ramelteon in the treatment of chronic insomnia and suggested that ramelteon
was … Our study suggested that ramelteon was not associated with adverse effects other than …

Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study.

GS Richardson, G Zammit… - Journal of Clinical …, 2009 - psychiatrist.com
… of ramelteon for up to 6 months in adults20,26 and older adults21,25 with chronic insomnia.
… group, the ability to interpret the effects of ramelteon on sleep from this study is limited. The …

Effects of longterm exposure to ramelteon, a melatonin receptor agonist, on endocrine function in adults with chronic insomnia

G Richardson, S Wang‐Weigand - … : Clinical and Experimental, 2009 - Wiley Online Library
effects of ramelteon, an MT 1 /MT 2 melatonin receptor agonist used to treat insomnia, on
endocrine function in adults with chronic … Subjects received either ramelteon 16 mg or placebo …

Ramelteon

A McGechan, K Wellington - CNS drugs, 2005 - Springer
chronic insomnia, ramelteoneffects. It also generally increased total sleep time and, where
assessed, sleep efficiency. ▲ In a first-night-effect model of transient insomnia, ramelteon