Renoprotective effects of low-dose valsartan in type 2 diabetic patients with diabetic nephropathy

K Suzuki, S Souda, T Ikarashi, S Kaneko… - Diabetes research and …, 2002 - Elsevier
… As the RAS activity may be accelerated more in patients with severe diabetic nephropathy
than in patients with incipient nephropathy, we interpreted that valsartan substantially reduced …

Effects of valsartan combined with α-lipoic acid on renal function in patients with diabetic nephropathy: a systematic review and meta-analysis

F Sun, D Jiang, J Cai - BMC endocrine disorders, 2021 - Springer
Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes,
valsartan … The purpose of this study was to evaluate the efficacy of valsartan combined …

Protective effects of aliskiren and valsartan in mice with diabetic nephropathy

W Wang, L Qiu, A Howard, N Solis… - Journal of the renin …, 2014 - journals.sagepub.com
… Our study indicates that aliskiren and/or valsartan protects against diabetic kidney disease
through multiple mechanisms, including decreasing podocyte injury, activation of profibrotic …

Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice

YF Dong, L Liu, ZF Lai, E Yamamoto… - Journal of …, 2010 - journals.lww.com
… , we examined the effect of aliskiren on type 2 diabetic nephropathy in detail and … diabetic
nephropathy. We obtained the evidence that aliskiren protected against diabetic nephropathy

Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy

J Galle, E Schwedhelm, S Pinnetti… - Nephrology Dialysis …, 2008 - academic.oup.com
… role in the pathophysiology of diabetic nephropathy, with … mg/g or with diabetic kidney disease,
regardless of their blood … ARBs) for type 2 diabetes mellitus (T2D) nephropathy [ 5 ]. This …

Effect of valsartan on kidney outcomes in people with impaired glucose tolerance

G Currie, MA Bethel, B Holzhauer… - Diabetes, Obesity …, 2017 - Wiley Online Library
diabetes mellitus is the most frequent cause of kidney failure leading to dialysis.The first
manifestation of diabetic nephropathy … 10 years of their diagnosis of diabetes).Microalbuminuria …

[PDF][PDF] Renal and metabolic effects of valsartan

T Ecder - The Anatolian Journal of Cardiology, 2014 - jag.journalagent.com
… of its blood pressure lowering effects in the patients having either diabetic and non-diabetic
nephropathy. In this review, the studies investigating the renal effects of valsartan will be …

Valsartan slows the progression of diabetic nephropathy in db/db mice via a reduction in podocyte injury, and renal oxidative stress and inflammation

G Zhou, AK Cheung, X Liu, Y Huang - Clinical science, 2014 - portlandpress.com
… Uninephrectomized db/db mice with diabetes developed overt nephropathy by 18 weeks of
… determine the effect of valsartan on the progression of established diabetic nephropathy in …

Effects of valsartan, benazepril and their combination in overt nephropathy of type 2 diabetes: A prospective, randomized, controlled trial

P Ruggenenti, M Trillini, D P. Barlovic… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aims To evaluate whether angiotensin‐converting enzyme (ACE) inhibitor and angiotensin II
receptor blocker (ARB) combination therapy is more nephroprotective than ACE inhibitor or …

Additive effect of ACE inhibition and angiotensin II receptor blockade in type I diabetic patients with diabetic nephropathy

P Jacobsen, S Andersen, BR Jensen… - Journal of the …, 2003 - journals.lww.com
… The additive effect of benazepril and valsartan on albuminuria, BP, and plasma … valsartan
alone. Therefore, the potential role of dual blockade depends on whether the observed effects