… ) and the breakdown of endogenous natriuretic peptides [eg sacubitril/valsartan (S/V)]. More
… in HF in terms of efficacy/effectiveness and safety in clinical trials and daily clinical practice. …

… , sacubitril/valsartan showed good safety and … sacubitril/valsartan is effective and safe
in the treatment of HFrEF patients but that it has little benefit in HFpEF patients. Sacubitril/valsartan …

… ejection fraction in the Sacubitril/Valsartan group was higher … cardiac events in the
Sacubitril/Valsartan group was lower … obvious advantage of the Sacubitril/Valsartan group over the …

… We evaluated heterogeneity in the effect of sacubitril/valsartan on these efficacy and safety
outcomes in selected subgroups of clinical concern: patients with baseline systolic blood …

… Background: Women are underrepresented in sacubitril/ valsartan (SV) clinical trials. The
aim of this study was to assess sex-specific differences in efficacy, tolerability, and safety of SV …

… This study sought to evaluate the efficacy and safety of sacubitril/valsartan according to dose
level achieved in the PIONEER-HF (Comparison of Sacubitril/Valsartan Versus Enalapril on …

… The efficacy and safety outcomes of sacubitril-valsartan were … : (i) RCTs with a sacubitril-valsartan
(Sac/Val) group and a … (iii) RCTs analysing primary efficacy outcomes, including death …

… ambulatory BP compared with valsartan12 or placebo.13 … Compared with olmesartan,
sacubitril/valsartan has been … the efficacy and safety of sacubitril/valsartan compared with …

… the benefit of sacubitril and/or valsartan from chronic HFrEF … However, the role of sacubitril
and/or valsartan in post- ST-… the safety and efficacy of sacubitril and/or valsartan versus a …

… postoperative application of sacubitril/valsartan in patients … Several studies have demonstrated
that sacubitril/valsartan is … clarify the efficacy and safety of sacubitril/valsartan following …