Importance of the field: Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon
that carries considerable burden and morbidity for patients and presents a constant …

… -to-severe ulcerative colitis. We aimed to compare the relative efficacy and safety of biologics
… efficacious for the treatment of ulcerative colitis in phase 3 randomised clinical trials (RCTs) …

Background: Approximately 25% of patients with ulcerative colitis [UC] experience a severe
flare requiring steroid therapy to avoid colectomy. We performed a systematic review and …

Background & Aims Interleukin 23 contributes to the pathogenesis of ulcerative colitis (UC).
We investigated the effects of mirikizumab, a monoclonal antibody against the p19 subunit of …

… efficacy and safety of etrasimod in patients with moderately to severely active ulcerative colitis
… The current study aimed to determine the safety and efficacy of etrasimod in patients with …

… The safety and efficacy of vedolizumab IV is well-established for both induction and … efficacy
and safety results from the phase 3 VISIBLE 1 trial, which evaluated the efficacy and safety of …

… The safety and efficacy of adalimumab in the treatment of … Here, we report the results of a
52-week efficacy and safety … was to compare the efficacy and safety results of adalimumab for …

… Its efficacy and safety have been demonstrated in three … efficacy and safety of tofacitinib
and to define its role and position in the treatment algorithms for patients with ulcerative colitis. …

… -blind study evaluated the efficacy and safety of the anti-α 4 β 7 antibody abrilumab in
patients with moderate-to-severe ulcerative colitis despite treatment with conventional therapies. …

… disease (IBD) is a disorder of the gastrointestinal tract that includes ulcerative colitis (UC) …
≥65 years, we provide safety and efficacy data for GEMINI patients in this age group as well. …