Elagolix treatment in women with heavy menstrual bleeding-associated with uterine fibroids: Efficacy and safety results from a phase 2b study

JA Simon, EA Stewart, C Owens, WR Duan, J Gao… - Fertility and …, 2017 - fertstert.org
Objective Elagolix is an oral, non-peptide, gonadotropin-releasing hormone antagonist.
Elagolix was evaluated in premenopausal women with heavy menstrual bleeding (HMB;> 80mL/…

Contemporary management of uterine fibroids: focus on emerging medical treatments

SS Singh, L Belland - Current medical research and opinion, 2015 - Taylor & Francis
… artery embolisation for the treatment of symptomatic uterine fibroids (HOPEFUL study): main
results on medium-term safety and efficacy. BJOG: an International Journal of Obstetrics and …

Phase 3 trial results: efficacy and safety of elagolix in a subset of women with uterine fibroids and adenomyosis

O Muneyyirci-Delale, DF Archer, JHJ Kim, R Liu… - Journal of Minimally …, 2019 - Elsevier
… (HMB) and dysmenorrhea, and commonly co-exists with uterine fibroids (UF). This analysis
evaluated the efficacy and safety of elagolix, an oral, gonadotropin-releasing hormone …

Uterine fibroids: an update on current and emerging medical treatment options

M Farris, C Bastianelli, E Rosato, I Brosens… - … and clinical risk …, 2019 - Taylor & Francis
Uterine fibroids are the most common gynecological disorder, … stages of testing in women
with fibroids. Another fundamental … The study confirmed the efficacy of UPA in controlling pain …

Mifepristone for uterine fibroids

M Tristan, LJ Orozco, A Steed… - Cochrane Database …, 2012 - cochranelibrary.com
… To determine the efficacy and safety of mifepristone for the management of uterine fibroids
… This review includes three trials and 112 women with uterine fibroids under mifepristone …

High-intensity focused ultrasound treatment for symptomatic uterine fibroids: a systematic review and meta-analysis

L Yan, H Huang, J Lin, R Yu - International journal of hyperthermia, 2022 - Taylor & Francis
… We herein evaluated the therapeutic efficacy of HIFU in the treatment of uterine fibroids in
terms of the SSS, HRQoL score and re-intervention rate and compared HIFU with UAE and …

Uterine fibroids and evidence-based medicine—not an oxymoron

EA Stewart - New England Journal of Medicine, 2012 - Mass Medical Soc
… of uterine fibroids noted, “Despite the prevalence and possible complications of uterine
fibroids… of a unique intermittent therapy that maximizes efficacy while minimizing safety concerns. …

Ultrasound-guided high intensity focused ultrasound for the treatment of gynaecological diseases: a review of safety and efficacy

L Zhang, W Zhang, F Orsi, W Chen… - International Journal of …, 2015 - Taylor & Francis
… Many studies have shown that HIFU is safe and effective in treating patients with uterine
fibroids, adenomyosis, cervicitis or vulvar diseases. Both magnetic resonance imaging-guided …

Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study

E Roshdy, V Rajaratnam, S Maitra… - … journal of women's …, 2013 - Taylor & Francis
… clinical trial, we set out to evaluate the efficacy and safety of oral green tea extract (EGCG)
in … clinical trial was designed to evaluate the efficacy and safety of oral green tea extract (EGCG…

[HTML][HTML] Ulipristal acetate compared with leuprorelin acetate for Japanese women with symptomatic uterine fibroids: a phase III randomized controlled trial

Y Osuga, Y Nakano, Y Yamauchi, M Takanashi - Fertility and sterility, 2021 - Elsevier
… To evaluate the efficacy and safety of ulipristal acetate (UPA) for uterine fibroids (UFs), a
phase III study was conducted with leuprorelin (LEU) as a comparator. This is the first …