… with chemoradiation, while … efficacy), we will discuss combinations of targeted agents with
radiation, which have the potential to eliminate conventional chemotherapy in chemoradiation …

… with radiation (RT) or chemoradiation therapy (CRT). Despite a … RT or CRT are combined
with targeted agents. The current review … -targeted therapy approaches with improved efficacy. …

… of chemoradiation has resulted in unacceptable toxicity. As such, there have recently been
increased efforts to combine chemoradiation with molecularly targeted … increased efficacy that …

… chemotherapy despite a lack of efficacy data in patients with rectal cancer. Future work is
likely to focus on preoperative chemotherapy before chemoradiation as a strategy for improving …

… , making them attractive anti-cancer agents for PC, This review … ability to induce the response
of chemo-radiation therapy. … out to identify the agents that target Sp proteins (especially 1&3…

… chemoradiation.In pancreatic cancer, two phase II trials evaluating the addition of bevacizumab
to chemoradiation … the safety and efficacy of bevacizumab with chemoradiation and its …

… By screening new drugs on the basis of monotherapy efficacy, we may fail to identify
agents that ultimately provide their strongest clinical impact by exploiting basic principles of …

… A recent analysis of efficacy and patterns of failure from this study showed that locoregional
… assessment as an end-point for trials of biologically targeted agents in addition to CRT. …

… Given that the focus of this article is on EGFR targeted agents with radiation and
chemoradiation, we will briefly discuss the interaction between EGFR inhibitors and chemotherapy. …

… , the efficacy of these agents has been mixed when studied in the metastatic setting or in
combination with chemoradiation. In this review, the history of the development of targeted …