Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study

EEW Cohen, DW Davis, TG Karrison, TY Seiwert… - The lancet …, 2009 - thelancet.com
… agents have displayed modest efficacy. Vascular endothelial … I/II study we combined an
EGFR inhibitor, erlotinib, with an … to be halted for lack of efficacy. Otherwise an additional 24 …

Comparison of afatinib and erlotinib combined with bevacizumab in untreated stage IIIB/IV epidermal growth factor receptor-mutated lung adenocarcinoma patients: a …

SH Lee, YC Lin, LC Chiu, JS Ju… - Therapeutic …, 2022 - journals.sagepub.com
… The efficacy and safety of bevacizumab in combination with first- or second-generation
EGFR-TKIs for the treatment of advanced EGFR-mutated NSCLC patients have been explored in …

[HTML][HTML] Phase II study of bevacizumab in combination with 1st-line chemotherapy or 2nd-line erlotinib in non-squamous NSCLC (NS-NSCLC) patients with …

B Besse, S Le Moulec, H Senellart, J Mazieres… - Annals of …, 2012 - Elsevier
… to bevacizumab treatment based on safety data. The non-comparative phase II BRAIN trial
(NCT00800202) is the first study to assess the efficacy/safety of bevacizumab in combination

[PDF][PDF] Bevacizumab plus erlotinib in Chinese patients with untreated, EGFR-mutated, advanced NSCLC (ARTEMIS-CTONG1509): a multicenter phase 3 study

Q Zhou, CR Xu, Y Cheng, YP Liu, GY Chen, JW Cui… - Cancer cell, 2021 - cell.com
… We compared the efficacy and safety of bevacizumab and erlotinib … Our results were consistent
with NEJ026, where the combination of bevacizumab and erlotinib significantly prolonged …

[HTML][HTML] … with untreated metastatic epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma receiving first-line erlotinib and bevacizumab combination …

CC Wang, LC Chiu, PH Tung, SCH Kuo, CH Chu… - Oncology and …, 2021 - Springer
… Only East Asian patients were recruited and analyzed in this study; whether this combination
has similar efficacy and toxicities in racial groups other than East Asians must be explored …

Bevacizumab with or without erlotinib as maintenance therapy in patients with metastatic colorectal cancer (GERCOR DREAM; OPTIMOX3): a randomised, open-label …

C Tournigand, B Chibaudel, B Samson… - The Lancet …, 2015 - thelancet.com
… We assessed whether the combination of erlotinib, an EGFR tyrosine kinase inhibitor,
with bevacizumab could increase the efficacy of maintenance therapy in patients with …

[HTML][HTML] Combined effects of bevacizumab with erlotinib and irradiation: a preclinical study on a head and neck cancer orthotopic model

A Bozec, A Sudaka, JL Fischel, MC Brunstein… - British journal of …, 2008 - nature.com
… these approaches, we evaluated in vivo the anti-tumour efficacy of the anti-angiogenic
compound bevacizumab, a highly specific monoclonal antibody directed against the vascular …

Targeted therapy with bevacizumab and erlotinib tailored to the molecular profile of patients with recurrent glioblastoma. Preliminary experience

QG D'Alessandris, N Montano, T Cenci, M Martini… - Acta …, 2013 - Springer
efficacy and safety of a targeted therapeutic approach in which administration of bevacizumab
and erlotinib … Our results with the combination of bevacizumab/erlotinib are significantly …

[HTML][HTML] Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression

H Li, K Takayama, S Wang, Y Shiraishi… - Cancer chemotherapy …, 2014 - Springer
… to improve efficacy and avoid the … of combined agents to erlotinib is difficult to detect in
erlotinib-sensitive tumor, we investigated the efficacy of erlotinib plus bevacizumab in erlotinib-…

[HTML][HTML] Addition of bevacizumab to erlotinib as first-line treatment of patients with EGFR-mutated advanced nonsquamous NSCLC: the BEVERLY multicenter …

MC Piccirillo, L Bonanno, MC Garassino… - Journal of Thoracic …, 2022 - Elsevier
… real-world efficacy, it is … , bevacizumab plus erlotinib might be considered among the first-line
therapeutic option in patients who cannot receive osimertinib and the strategy of combining