Impact of EGFR Mutation Detection Methods on the Efficacy of Erlotinib in Patients with Advanced EGFR-Wild Type Lung Adenocarcinoma

JS Tseng, CL Wang, MS Huang, CY Chen, CY Chang… - PloS one, 2014 - journals.plos.org
… methods on the efficacy of erlotinib treatment. For the Group-II patients, we assessed their
EGFR mutation status by DS and calculated the number of EGFR mutations that would not be …

EGFR mutation frequency and effectiveness of erlotinib: a prospective observational study in Danish patients with non-small cell lung cancer

B Weber, H Hager, BS Sorensen, T McCulloch… - Lung Cancer, 2014 - Elsevier
… However, after January 2011, EGFR mutation testing was … EGFR mutated patients in our
study (1.5%) received erlotinib as first-line treatment. All patients were treated with erlotinib until …

Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene mutations

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… their efficacy in patients with rare EGFR mutations. While gefitinib, erlotinib, and afatinib have
proven efficacy in patients with the two major mutations in the EGFR gene (ie, the classical …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn… - Cancer Research and …, 2019 - synapse.koreamed.org
… Our study confirms the previous efficacy data of afatinib for NSCLC harboring uncommon
EGFR mutations other than T790M. Compared with gefitinib and erlotinib, afatinib treatment …

Efficacy of EGFR tyrosine kinase inhibitors in patients with EGFR-mutated non–small-cell lung cancer: a meta-analysis of 13 randomized trials

F Petrelli, K Borgonovo, M Cabiddu, S Barni - Clinical lung cancer, 2012 - Elsevier
… by EGFR mutation status. This meta-analysis demonstrated that EGFR mutations predict
response to EGFR … , NSCLCs harboring EGFR mutations derive greater benefit from erlotinib or …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
EGFR mutation screening, it also examined the influence of EGFR mutations on the efficacy
of … can be the most important predictive factor for efficacy of TK inhibitors, so we analyzed …

[HTML][HTML] Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial

JP Wang, CY Wu, YC Yeh, YM Shyr, YY Wu, CY Kuo… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… Our study first found that EGFR mutations are common in … that EGFR mutations can predict
gemcitabine plus erlotinib … detected between EGFR mutations and the efficacy of erlotinib in …

[HTML][HTML] Effectiveness of gefitinib against non–small-cell lung cancer with the uncommon EGFR mutations G719X and L861Q

S Watanabe, Y Minegishi, H Yoshizawa… - Journal of thoracic …, 2014 - Elsevier
efficacy of gefitinib in patients with uncommon mutations, we conducted a post-hoc analysis
of the NEJ002, which compared gefitinib … advanced NSCLC with activating EGFR mutations. …

Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients

L Xiong, Y Lou, H Bai, R Li, J Xia… - Journal of …, 2020 - journals.sagepub.com
… In the present study, we compared the efficacy of erlotinib, a first-generation EGFR-TKI,
with … that erlotinib as neoadjuvant therapy was well-tolerated and beneficial in EGFR-mutant

Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation

R Porta, JM Sanchez-Torres, L Paz-Ares… - European …, 2011 - Eur Respiratory Soc
… the efficacy of erlotinib in this … the efficacy of erlotinib in a series of patients with brain
metastases from NSCLC and its association with the presence of activating mutations in the EGFR