Efficacy vs. effectiveness: erlotinib in previously treated non-small-cell lung cancer

N Sheikh, CR Chambers - Journal of Oncology Pharmacy …, 2013 - journals.sagepub.com
… PFS was calculated as the time from start of erlotinib until the time of discontinuation of
erlotinib. Duration of response was calculated as the time from when measurement criteria were …

Clinical impact of gastric acid-suppressing medication use on the efficacy of erlotinib and gefitinib in patients with advanced non–small-cell lung cancer harboring …

Y Zenke, K Yoh, S Matsumoto, S Umemura, S Niho… - Clinical Lung Cancer, 2016 - Elsevier
… In this study, concurrent use of AS did not affect the efficacy or toxicity of erlotinib and
gefitinib in patients with advanced NSCLC harboring EGFR mutations. It provides data that can …

An evaluation of the possible interaction of gastric acid suppressing medication and the EGFR tyrosine kinase inhibitor erlotinib

JF Hilton, D Tu, L Seymour, FA Shepherd, PA Bradbury - Lung cancer, 2013 - Elsevier
… may lower the efficacy of erlotinib as AS suppressive medications have the potential to reduce
the absorption of the medication. This potential interaction is not restricted to erlotinib. For …

Efficacy and safety of first-line erlotinib in elderly patients with advanced non-small cell lung cancer

O Merimsky, CK Cheng, JSK Au… - Oncology …, 2012 - spandidos-publications.com
… or radiotherapy, and were ineligible for other erlotinib trials (14). A … the favourable efficacy
and safety profile of erlotinib in a large … patients who received erlotinib as their first line therapy. …

[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study

K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
… The aim of this study was to evaluate the efficacy and safety of Erlotinib in Japanese
patients with previously treated non-small cell lung cancer (NSCLC). Available tumor biopsy …

Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study

WKA Yung, JJ Vredenburgh, TF Cloughesy… - Neuro …, 2010 - academic.oup.com
Erlotinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is active
in glioblastoma. We evaluated erlotinib efficacy … and/or concomitant use of enzyme-inducing …

The use of erlotinib in daily practice: a study on adherence and patients' experiences

L Timmers, CCLM Boons, D Mangnus, JE Moes… - BMC cancer, 2011 - Springer
use of erlotinib in daily practice and the various aspects that govern adherence. We hypothesize
that side-effects play an important role in the way patients use erlotinibuse of erlotinib in …

High efficacy of erlotinib in Taiwanese NSCLC patients in an expanded access program study previously treated with chemotherapy

RP Perng, CH Yang, YM Chen, GC Chang, MC Lin… - Lung Cancer, 2008 - Elsevier
… This analysis was based on 299 patients who received at least one dose of erlotinib. The
best response rates were a 29% partial response and 44% stable disease in 273 patients who …

[PDF][PDF] Erlotinib for the treatment of relapsed non-small cell lung cancer

C McLeod, A Bagust, A Boland… - Health Technol …, 2009 - scholar.archive.org
… Currently there are no trials that directly compare erlotinib with any other second-… use of
docetaxel. From these data the manufacturer concludes that erlotinib has similar clinical efficacy

Erlotinib: a pharmacoeconomic review of its use in advanced non-small cell lung cancer

KA Lyseng-Williamson - Pharmacoeconomics, 2010 - Springer
… The efficacy of erlotinib in the treatment of advanced NSCLC is well established.[3–5] In
current international,[6] European[7,8] and US[9] treatment guidelines, a platinum-based …