Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non–small-cell lung cancer and a performance status of 2
R Lilenbaum, R Axelrod, S Thomas… - Journal of Clinical …, 2008 - ascopubs.org
… To the best of our knowledge, this is the first trial to provide information about the efficacy
and safety of first-line treatment with erlotinib in a controlled population of PS 2patients with …
and safety of first-line treatment with erlotinib in a controlled population of PS 2patients with …
Open, randomized, multi-center phase II study comparing efficacy and tolerability of Erlotinib vs. Carboplatin/Vinorelbin in elderly patients (> 70 years of age) with …
DF Heigener, KM Deppermann, JV Pawel, JR Fischer… - Lung Cancer, 2014 - Elsevier
… -study was also negative regarding Erlotinib as first-line treatment in NSCLC: In this study,
treatment-naïve NSCLC-patients either received Erlotinib daily or conventional chemotherapy …
treatment-naïve NSCLC-patients either received Erlotinib daily or conventional chemotherapy …
Study of efficacy and safety of pulsatile administration of high‐dose gefitinib or erlotinib for advanced non‐small cell lung cancer patients with secondary drug …
Y Zhu, Y Du, H Liu, T Ma, Y Shen, Y Pan - Thoracic cancer, 2016 - Wiley Online Library
… All 42 patients showed PD after having received gefitinib or erlotinib for a year prior to this
study… The median PFS was 31 months in the gefitinib and 24 months in the erlotinib group. No …
study… The median PFS was 31 months in the gefitinib and 24 months in the erlotinib group. No …
Assessment of erlotinib as adjuvant chemoprevention in high-risk head and neck cancer patients
EL Rosenthal, TK Chung, WR Carroll… - Annals of surgical …, 2014 - Springer
… Despite the limitations of our efficacy analysis, the current study demonstrates an important
first step in evaluating erlotinib as a potential therapy for high-risk patients after salvage …
first step in evaluating erlotinib as a potential therapy for high-risk patients after salvage …
First-line erlotinib therapy until and beyond response evaluation criteria in solid tumors progression in Asian patients with epidermal growth factor receptor mutation …
K Park, CJ Yu, SW Kim, MC Lin, V Sriuranpong… - JAMA …, 2016 - jamanetwork.com
… of studying the efficacy of first-line erlotinib therapy in patients with activating EGFR
mutations. The concept of treatment beyond RECIST 1.1 progression and the use of plasma-based …
mutations. The concept of treatment beyond RECIST 1.1 progression and the use of plasma-based …
Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with erlotinib in patients with advanced solid tumors
AW Tolcher, P LoRusso, J Arzt, TA Busman… - Cancer chemotherapy …, 2015 - Springer
… an arm evaluating navitoclax combined with erlotinib, which included a dose escalation …
Patients with documented cancers for whom erlotinib therapy was appropriate received erlotinib …
Patients with documented cancers for whom erlotinib therapy was appropriate received erlotinib …
Evaluation of erlotinib in advanced non-small cell lung cancer: impact on the budget of a US health insurance plan
SD Ramsey, L Clarke, TV Kamath, D Lubeck - Journal of Managed Care …, 2006 - jmcp.org
… Assuming that erlotinib comprises 30% of second-line … are $382,418 with erlotinib and
$380,968 without erlotinib (difference… This budget impact model does not consider efficacy beyond …
$380,968 without erlotinib (difference… This budget impact model does not consider efficacy beyond …
Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer
DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
… In the present trial, the goal was to see whether sorafenib could improve the efficacy already
achieved with erlotinib. Preclinical and phase I data provide rationale for using these drugs …
achieved with erlotinib. Preclinical and phase I data provide rationale for using these drugs …
Treatment monitoring program for implementation of adherence to second-line erlotinib for advanced Non–Small-Cell lung cancer
… Erlotinib is currently approved for second-line therapy and … will probably lead to the
approval of erlotinib for the first-line … chemotherapy provided that the efficacy of oral therapy is …
approval of erlotinib for the first-line … chemotherapy provided that the efficacy of oral therapy is …
Cross-market cost-effectiveness analysis of erlotinib as first-line maintenance treatment for patients with stable non-small cell lung cancer
… was efficacious in both the intent-to-treat and stable disease populations. Patient … analysis
of erlotinib versus pemetrexed were to be performed, the comparable efficacy of erlotinib and …
of erlotinib versus pemetrexed were to be performed, the comparable efficacy of erlotinib and …