… II study to evaluate the efficacy and safety of gefitinib as first-line treatment for Korean patients with advanced pulmonary adenocarcinoma harboring EGFR mutations

DW Kim, SH Lee, JS Lee, MA Lee, JH Kang, SY Kim… - Lung cancer, 2011 - Elsevier
… As an exploratory objective, we analyzed the efficacy of gefitinib treatment according to
the EGFR mutation subtypes. Interestingly, in-frame exon 19 deletions were associated with …

The different efficacy of gefitinib or erlotinib according to epidermal growth factor receptor exon 19 and exon 21 mutations in Korean non-small cell lung cancer …

JM Sun, YW Won, ST Kim, JH Kim, YL Choi… - Journal of cancer …, 2011 - Springer
… (EGFR) mutations are associated with sensitivity to gefitinib or … EGFR mutations, exon 19
deletions and L858R mutations, and … NSCLC patients after treatment with gefitinib or erlotinib. …

[HTML][HTML] A retrospective comparison of the clinical efficacy of gefitinib, erlotinib, and afatinib in Japanese patients with non-small cell lung cancer

A Fujiwara, M Yoshida, H Fujimoto, H Nakahara… - Oncology …, 2018 - ncbi.nlm.nih.gov
… The aim of this study was to compare the effectiveness of gefitinib, erlotinib, and afatinib.
We retrospectively reviewed the records of 310 patients with the diagnosis of EGFR mutation-…

Icotinib is as efficacious as gefitinib for brain metastasis of EGFR mutated non-small-cell lung cancer

K Liu, G Jiang, A Zhang, Z Li, J Jia - BMC cancer, 2020 - Springer
… icotinib and gefitinib had similar efficacy for brain metastasis of EGFR mutated NSCLC.
Large randomized studies are suggested to further illuminate the effect of these two EGFR-TKIs …

[HTML][HTML] Therapeutic efficacy of gefitinib and erlotinib in patients with advanced lung adenosquamous carcinoma

Z Song, B Lin, L Shao, Y Zhang - Journal of the Chinese Medical …, 2013 - Elsevier
EGFR mutations.9, 10 However, no clinical study to evaluate efficacy of EGFR-TKIs and
mutation … ASC showing EGFR mutations have been reported with an EGFR mutation frequency …

… after first-line gefitinib therapy in EGFR mutation-positive advanced non-small cell lung cancer—data from a randomized Phase III study comparing gefitinib with …

E Miyauchi, A Inoue, K Kobayashi… - Japanese Journal of …, 2015 - academic.oup.com
EGFR TKI can lead to a good antitumor response. Thus, we evaluated … efficacy of such
chemotherapy after lack of gefitinib response for advanced NSCLC harboring EGFR mutations

Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis

T Yoshida, K Yamada, K Azuma, A Kawahara, H Abe… - Medical oncology, 2013 - Springer
… However, the efficacy of these agents against EGFR wild-type (-… efficacy in patients with
NSCLC whose EGFR mutation status had been confirmed and who all received 250 mg gefitinib

Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations

E Ichihara, K Hotta, N Takigawa, K Kudo, Y Kato… - Lung Cancer, 2013 - Elsevier
… the association between BSA and the efficacy of gefitinib monotherapy found in the current
… of gefitinib. This suggests the importance of dose-adjustment by BSA in gefitinib monotherapy…

Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell …

T Sone, K Kasahara, H Kimura, K Nishio… - Cancer, 2007 - Wiley Online Library
… predictors of gefitinib efficacy. In the current study, we evaluated the EGFR mutation status
and … to assess their predictive value in regard to the efficacy of gefitinib in this population. …

Evaluation of gefitinib efficacy according to body surface area in patients with non-small cell lung cancer harboring an EGFR mutation

S Igawa, M Kasajima, M Ishihara, M Kimura… - Cancer chemotherapy …, 2014 - Springer
… therapy according to BSA, based on the results of the present study, the efficacy of gefitinib
therapy does not depend on the BSA of patients with NSCLC harboring an EGFR mutation. …