[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta …

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
… In the EGFR mutation status subgroup, we also … efficacy of gefitinib and erlotinib. However,
our results indirectly prove that both gefitinib and erlotinib are more suitable for treating EGFR

Impact of smoking history on the efficacy of gefitinib in patients with non-small cell lung cancer harboring activating epidermal growth factor receptor mutations

S Igawa, J Sasaki, S Otani, M Ishihara, A Takakura… - Oncology, 2015 - karger.com
… Variables including age, gender, smoking status, performance status (PS), type of EGFR
mutation, clinical stage at the start of gefitinib therapy, presence/absence of brain metastasis, …

Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating epidermal growth factor receptor mutation: Review of the evidence

C Gridelli, F De Marinis, M Di Maio, D Cortinovis… - Lung Cancer, 2011 - Elsevier
… In the subgroup of 437 patients analyzed for the presence of EGFR mutation, there was a
significant interaction between treatment efficacy and EGFR mutation status. Namely, …

The safety and efficacy of gefitinib versus platinum-based doublets chemotherapy as the first-line treatment for advanced non-small-cell lung cancer patients in East …

CH Chang, KY Chen, Y Young-Xu, T Kurth, EJ Orav… - Lung Cancer, 2008 - Elsevier
… Treatment arms with gefitinib 250mg/day and platinum-based doublets chemotherapy …
estimates for efficacy and safety outcomes of interest. RESULTS: We identified 7 gefitinib and 41 …

[HTML][HTML] The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer

XT Zhang, LY Li, XL Mu, QC Cui, XY Chang, W Song… - Annals of oncology, 2005 - Elsevier
… the efficacy of gefitinib and the epidermal growth factor receptor (EGFR) mutation to gefitinib
… had failed at least one platinum-based regimen received gefitinib 250 mg once daily. The …

EGFR mutations and pAKT expression as potential predictors of gefitinib efficacy in non-small cell lung cancer (NSCLC) patients (pts)

VM Villaflor, L Buckingham, M Gale, J Coon… - Journal of Clinical …, 2005 - ascopubs.org
gefitinib (GEF). The goal of this study was to assess EGFR mutations, as well as expression
of EGFR and related molecules by immunohistochemistry (IHC) as predictors of GEF efficacy

Efficacy of gefitinib at reduced dose in EGFR mutant non-small cell lung carcinoma

WC Kwok, JCM Ho, TCC Tam, MMS Lui… - Anti-Cancer …, 2019 - journals.lww.com
efficacy could still be maintained. Clinical data on efficacy of reduced dose gefitinib treatment
… NSCLC patients with sensitizing EGFR mutations, trough concentration of gefitinib was not …

… of chemotherapy and gefitinib as first‐line treatment for patients with advanced lung adenocarcinoma and sensitive EGFR mutations: a randomized controlled trial

B Han, B Jin, T Chu, Y Niu, Y Dong, J Xu… - … journal of cancer, 2017 - Wiley Online Library
… Our study examined the efficacy and safety of gefitinib combined with carboplatin and
pemetrexed for first-line treatment of advanced NSCLC with sensitive EGFR mutations. The study …

[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
EGFR mutation, we also found no difference between the 2 EGFR TKIs in the comparison of
antitumor effectiveness… that both gefitinib and erlotinib are more suitable for EGFR mutation–…

[HTML][HTML] Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations

W Liang, X Wu, W Fang, Y Zhao, Y Yang, Z Hu, C Xue… - PloS one, 2014 - journals.plos.org
… , gefitinib, afatinib and icotinib shared equivalent efficacy but presented different efficacy-toxicity
pattern for EGFR-mutated … Erlotinib and afatinib revealed potentially better efficacy but …