[HTML][HTML] Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas
Z Liang, J Zhang, X Zeng, J Gao, S Wu, T Liu - BMC cancer, 2010 - Springer
… This study was designed to investigate EGFR protein expression, EGFR copy number and
EGFR mutations in lung adenocarcinomas, to explore the relationship of the three markers. …
EGFR mutations in lung adenocarcinomas, to explore the relationship of the three markers. …
Prognostic and predictive implications of EGFR mutations, EGFR copy number and KRAS mutations in advanced stage lung adenocarcinoma
L Bonanno, M Schiavon, G Nardo… - Anticancer …, 2010 - ar.iiarjournals.org
… This study examined both EGFR and KRAS mutations, and EGFR gene copy number in a
clinically selected population of patients with advanced stage lung adenocarcinoma to …
clinically selected population of patients with advanced stage lung adenocarcinoma to …
EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression
… In conclusion, lung adenocarcinoma with EGFR mutations is a distinct biological subset as
… high response rate to EGFR TKIs. Amplification of EGFR in NSCLC with EGFR mutation is …
… high response rate to EGFR TKIs. Amplification of EGFR in NSCLC with EGFR mutation is …
… growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: a chromogenic in …
JWC Chang, HP Liu, MH Hsieh, YF Fang, MS Hsieh… - Lung Cancer, 2008 - Elsevier
… suggest Increased EGFR copy number was highly correlated with EGFR mutation in
adenocarcinoma. Although it is less correlated with TKI responsiveness when compared with EGFR …
adenocarcinoma. Although it is less correlated with TKI responsiveness when compared with EGFR …
[HTML][HTML] EGFR-activating mutations, DNA copy number abundance of ErbB family, and prognosis in lung adenocarcinoma
… In this study, EGFR-activating mutation status and DNA copy number … in 261 lung
adenocarcinomas. The associations between DNA copy number abundances of ErbB family, EGFR-…
adenocarcinomas. The associations between DNA copy number abundances of ErbB family, EGFR-…
… features and prognostic implications of epidermal growth factor receptor (EGFR) gene copy number and protein expression in non-small cell lung cancer
YK Jeon, SW Sung, JH Chung, WS Park, JW Seo… - Lung cancer, 2006 - Elsevier
… cancer, namely, the decrease in HER2 gene copy number in invasive ductal carcinoma relative
to ductal carcinoma … the possible heterogeneity of EGFR amplification in lung cancer, our …
to ductal carcinoma … the possible heterogeneity of EGFR amplification in lung cancer, our …
[HTML][HTML] EGFR and HER2 gene copy number and response to first-line chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)
F Cappuzzo, C Ligorio, L Toschi, E Rossi… - Journal of Thoracic …, 2007 - Elsevier
… This study suggested that EGFR expression and gene copy number, HER2 gene copy number…
Prospective phase III trials should compare standard chemotherapy with a TKI in selected …
Prospective phase III trials should compare standard chemotherapy with a TKI in selected …
[HTML][HTML] Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib
FR Hirsch, M Varella-Garcia, F Cappuzzo, J McCoy… - Annals of …, 2007 - Elsevier
… The current study demonstrated that FISH analysis for EGFR gene copy number in combination
with IHC assessment for EGFR protein is a useful paradigm for selection of advanced …
with IHC assessment for EGFR protein is a useful paradigm for selection of advanced …
EGFRvIII mutation in lung cancer correlates with increased EGFR copy number
H Sasaki, O Kawano, K Endo, H Yukiue… - Oncology …, 2007 - spandidos-publications.com
… To determine the EGFR mutation status in Japanese lung carcinoma for screening and
diagnostic purpose, we wanted to develop a faster and easier method to detect EGFRvIII …
diagnostic purpose, we wanted to develop a faster and easier method to detect EGFRvIII …
EGFR gene copy number in adenocarcinoma of the lung by FISH analysis: investigation of significantly related factors on CT, FDG-PET, and histopathology
… lung adenocarcinoma or BAC at Seoul National University Hospital. Among them, we selected
142 patients with EGFR gene copy number … the Lung Cancer Tissue Bank of the Cancer …
142 patients with EGFR gene copy number … the Lung Cancer Tissue Bank of the Cancer …
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