… Growing clinical experience with patients whose tumours harbour EGFR exon 20 insertions
… to EGFR TKIs. Despite the prevalence and biological importance of EGFR exon 20 insertions…

… of patients with lung cancers carrying EGFR exon 20 insertions. … EGFR mutations, the
clinical outcomes of lung cancers harboring EGFR exon 20 insertions would be similar to EGFR …

… of EGFR mutations in NSCLC, low frequency EGFR exon 20 … novo resistance to targeted
EGFR inhibitors and correlate with a … EGFR exon 20 insertion selective inhibitors in lung cancer …

… A) Impact of deletions and insertions on EGFR activation, and incidence of EGFR exon 20
insertions … 2019); B) Potential treatment strategies in EGFR exon 20 insertions lung tumors. …

… criteria were fulfilled: wild type EGFR, EGFR del-19 alone, or EGFR L858R in exon 21 alone.
A rare mutation was defined as any mutation other than del-19 or L858R in exon 21, and a …

… Sensitivity of EGFR exon 20 insertion mutations to EGFR TKIs in vitro … or response to
EGFR TKIs of exon 20 insertion mutations, we studied representative EGFR exon 20 mutations …

… that patients with lung cancer harboring an EGFR exon 19 … Our finding that 1% of EGFR-mutant
lung cancers harbor exon 19 … In contrast, an EGFR sequencing of a large cohort of Asian …

… growth factor receptor (EGFR) mutations other than common exon 19 deletions and … EGFR
exon 18 and/or exon 20 mutations were collected from 10 117 non-small-cell lung cancer (…

Aim: To estimate real-world (rw) outcomes for first-line therapy in patients with advanced
EGF receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC), focusing on specific …

… the insertion mutation at exon 20 is related to gefitinib resistance. We investigated the exon
20 EGFR mutation statuses in 322 surgically treated non-small cell lung cancer cases. Two …