[HTML][HTML] Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop
…, R Stahel, European EGFR Workshop Group - Journal of Thoracic …, 2010 - Elsevier
… of patients for EGFR mutations is feasible and results in … The QA results should also be
reported to the clinician. If a … is EGFR mutation positive, and a standard EGFR mutation test has …
reported to the clinician. If a … is EGFR mutation positive, and a standard EGFR mutation test has …
EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples
G Ellison, G Zhu, A Moulis, S Dearden… - Journal of clinical …, 2013 - jcp.bmj.com
… Testing for mutations in EGFR is therefore an important step in the treatment-decision pathway.
We reviewed reported methods for EGFR mutation testing … while test results are awaited. …
We reviewed reported methods for EGFR mutation testing … while test results are awaited. …
[HTML][HTML] An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting
K Goto, M Satouchi, G Ishii, K Nishio, K Hagiwara… - Annals of oncology, 2012 - Elsevier
… The results of this study showed that all five EGFR mutation tests had comparable success
rates (over 90%) in FFPE samples. These were consistently high success rates given that the …
rates (over 90%) in FFPE samples. These were consistently high success rates given that the …
Worldwide Frequency of Commonly Detected EGFR Mutations
RP Graham, AL Treece, NI Lindeman… - … of pathology & …, 2018 - meridian.allenpress.com
… In conclusion, we provide results from the CAP proficiency testing on EGFR mutation
analysis that indicate the relative detection rate of EGFR mutations. Although not truly …
analysis that indicate the relative detection rate of EGFR mutations. Although not truly …
EGFR testing in lung cancer is ready for prime time
FR Hirsch, PA Bunn - The lancet oncology, 2009 - thelancet.com
… patients with EGFR mutations, so the time has surely come for EGFR mutation testing to enter
… In conclusion, recent results support the use of EGFR mutations as a selection criterion for …
… In conclusion, recent results support the use of EGFR mutations as a selection criterion for …
EGFR mutations and lung cancer
G da Cunha Santos, FA Shepherd… - Annual Review of …, 2011 - annualreviews.org
… Mutation at the TK domain of EGFR results in the destabilization … with EGFR mutation and
commonly harbors KRAS mutations (55… for EGFR mutation testing and therapy with EGFR TKIs. …
commonly harbors KRAS mutations (55… for EGFR mutation testing and therapy with EGFR TKIs. …
[HTML][HTML] Sample features associated with success rates in population-based EGFR mutation testing
CJ Shiau, JP Babwah, G da Cunha Santos… - Journal of Thoracic …, 2014 - Elsevier
… unselected series of EGFR mutation testing for patients with … related factors that influence
success in clinical EGFR testing. … The results used in this analysis are from consecutive EGFR …
success in clinical EGFR testing. … The results used in this analysis are from consecutive EGFR …
[HTML][HTML] EGFR mutation testing practices within the Asia Pacific region: results of a multicenter diagnostic survey
… the number of NSCLC patients who were tested for EGFR mutations at the surveyed sites,
to estimate the rate of EGFR mutation positivity in the tested samples: overall, and by NSCLC …
to estimate the rate of EGFR mutation positivity in the tested samples: overall, and by NSCLC …
EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression
… assays are susceptible to false-negative results due to admixed non-neoplastic cells but
EGFR fluorescence in situ hybridization assays are not, we speculate that a subset of …
EGFR fluorescence in situ hybridization assays are not, we speculate that a subset of …
[HTML][HTML] Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR
M Brevet, M Arcila, M Ladanyi - The Journal of Molecular Diagnostics, 2010 - Elsevier
… for EGFR mutation status. We provide a careful assessment of putative false-positive and
false-negative results, … of about 20% among adenocarcinomas tested at our institution). The …
false-negative results, … of about 20% among adenocarcinomas tested at our institution). The …
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