[HTML][HTML] Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

EL Stewart, SZ Tan, G Liu, MS Tsao - Translational lung cancer …, 2015 - ncbi.nlm.nih.gov
… transformation to small cell lung cancer in EGFR mutant NSCLC patients with acquired EGFR
TKI resistance, accounting for resistance in possibly up to 3% of the patients. Interestingly, …

Clinical outcomes in non‐small‐cell lung cancer patients with EGFR mutations: pooled analysis

L Paz‐Ares, D Soulières, I Melezínek… - Journal of cellular …, 2010 - Wiley Online Library
… setting, NSCLC patients with EGFR mutations have shown dramatic responses to EGFR TKIs.
… 132 Asian patients with EGFR mutations [67]. In a Spanish study involving 197 evaluable …

EGFR mutational status in a large series of Caucasian European NSCLC patients: data from daily practice

S Gahr, R Stoehr, E Geissinger, JH Ficker… - British journal of …, 2013 - nature.com
… In summary, our data on EGFR mutation status from a large German cohort of NSCLC patients
in the daily clinical practice are in agreement with data from other populations around the …

Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC)

K Kobayashi, K Hagiwara - Targeted oncology, 2013 - Springer
… ), such as epidermal growth factor receptor (EGFR) mutations [1–3], a fusion … EGFR
mutations in advanced NSCLC, which was the first experience to treat advanced NSCLC patients

[HTML][HTML] Overview of current systemic management of EGFR-mutant NSCLC

WH Hsu, JCH Yang, TS Mok, HH Loong - Annals of Oncology, 2018 - Elsevier
… of EGFR TKIs in EGFR-mutant lung cancer patients. The side-… patients with tumours
harbouring EGFR mutations, and established EGFR mutation status as the best biomarker for EGFR

[HTML][HTML] The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis

YL Zhang, JQ Yuan, KF Wang, XH Fu, XR Han… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… In order to obtain a more precise estimate of EGFR mutation prevalence in NSCLC
patients and patient subgroups, we conducted this systematic review and meta-analysis. …

Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients

JL Kuiper, DAM Heideman, E Thunnissen, MA Paul… - Lung cancer, 2014 - Elsevier
… receptor (EGFR)-mutation have … EGFR T790M-mutation in the majority of patients. Longitudinal
follow-up data are lacking. We retrospectively evaluated EGFR-mutated NSCLC-patients

A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer

HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
… In this retrospective study, we screened 5363 NSCLC patients to determine the
prevalence … EGFR mutation in Chinese lung cancer patients and their sensitivity to EGFR-TKIs. …

EGFR mutations and lung cancer

G da Cunha Santos, FA Shepherd… - Annual Review of …, 2011 - annualreviews.org
… More recent trials have suggested that for advanced NSCLC patients with EGFR mutant
tumors, initial therapy with a TKI instead of chemotherapy may be the best choice of treatment. …

[HTML][HTML] Large scale, prospective screening of EGFR mutations in the blood of advanced NSCLC patients to guide treatment decisions

C Mayo-de-Las-Casas, N Jordana-Ariza… - Annals of …, 2017 - Elsevier
… testing for EGFR mutations in the cfDNA of 1033 unselected advanced NSCLC patients at
presentation … Patients tested could not be biopsied, or the amount of cancer cells in biopsies or …