[HTML][HTML] … (EGFR) Mutations upon Progression on or after First-Line Therapy with a First- or Second-Generation EGFR Tyrosine Kinase Inhibitor in EGFR Mutation …
G Mountzios, A Koumarianou, A Bokas, D Mavroudis… - Cancers, 2021 - mdpi.com
… mutation, using the cobas EGFR Mutation Test v2 at the time of progression on or after
first-line first- or second-generation EGFR-… to determine the frequency of EGFR T790M-mediated …
first-line first- or second-generation EGFR-… to determine the frequency of EGFR T790M-mediated …
A Prospective Evaluation of Circulating Tumor Cells and Cell-Free DNA in EGFR-Mutant Non–Small Cell Lung Cancer Patients Treated with Erlotinib on a Phase II …
M Yanagita, AJ Redig, CP Paweletz, SE Dahlberg… - Clinical Cancer …, 2016 - AACR
… for noninvasive evaluation. This prospective trial evaluated CTCs and cfDNA in EGFR-mutant …
Experimental Design: EGFR-mutant NSCLC patients were enrolled in a phase II trial of …
Experimental Design: EGFR-mutant NSCLC patients were enrolled in a phase II trial of …
[HTML][HTML] Prospective evaluation of first-line erlotinib in advanced non-small cell lung cancer (NSCLC) carrying an activating EGFR mutation: A multicenter academic …
J De Grève, J Van Meerbeeck, JF Vansteenkiste… - PLoS …, 2016 - journals.plos.org
… the use of EGFR tyrosine kinase inhibition (TKI) as a first line treatment of choice for advanced
adenocarcinoma of the lung carrying an activating EGFR mutation. The mutation rate in …
adenocarcinoma of the lung carrying an activating EGFR mutation. The mutation rate in …
[HTML][HTML] Impact of systematic EGFR and KRAS mutation evaluation on progression-free survival and overall survival in patients with advanced non–small-cell lung …
… sarcoma (KRAS) mutation status, although associated with EGFR- tyrosine kinase inhibitor
(… The prospective Evaluation of the EGFR Mutation status for the administration of EGFR-TKIs …
(… The prospective Evaluation of the EGFR Mutation status for the administration of EGFR-TKIs …
Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers
M Offin, H Rizvi, M Tenet, A Ni, F Sanchez-Vega… - Clinical Cancer …, 2019 - AACR
… We identified all patients with metastatic EGFR exon19del or L858R-mutant lung cancers …
In this analysis, we evaluated the utility of TMB as a predictive biomarker in EGFR-mutant lung …
In this analysis, we evaluated the utility of TMB as a predictive biomarker in EGFR-mutant lung …
Clinical Benefit of Tyrosine Kinase Inhibitors in Advanced Lung Cancer with EGFR‐G719A and Other Uncommon EGFR Mutations
… It is imperative to rigorously and prospectively evaluate such strategies vis‐à‐vis emerging
data for EGFR‐T790M active and central nervous system–penetrant osimertinib (phase II trial …
data for EGFR‐T790M active and central nervous system–penetrant osimertinib (phase II trial …
[HTML][HTML] Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA)
H Kimura, M Suminoe, K Kasahara, T Sone… - British journal of …, 2007 - nature.com
… was to evaluate the usefulness of EGFR mutation status in … EGFR mutation status was
determined by a direct sequencing method and by Scorpion Amplification Refractory Mutation …
determined by a direct sequencing method and by Scorpion Amplification Refractory Mutation …
… therapy until and beyond response evaluation criteria in solid tumors progression in Asian patients with epidermal growth factor receptor mutation–positive non–small …
K Park, CJ Yu, SW Kim, MC Lin, V Sriuranpong… - JAMA …, 2016 - jamanetwork.com
… EGFR mutations in plasma and outcomes was also a secondary end point. Tissue EGFR
mutation … by central testing if feasible using the cobas 4800 EGFR tissue test (Roche). Baseline …
mutation … by central testing if feasible using the cobas 4800 EGFR tissue test (Roche). Baseline …
[HTML][HTML] Evaluation of plasma EGFR mutation as an early predictor of response of erlotinib plus bevacizumab treatment in the NEJ026 study
T Fukuhara, H Saito, N Furuya, K Watanabe… - …, 2020 - thelancet.com
… (BE)-treated NSCLC patients with EGFR mutations had significantly better progression-free …
a prospective analysis of the relationship between the mutational status of EGFR in plasma …
a prospective analysis of the relationship between the mutational status of EGFR in plasma …
[HTML][HTML] Prospective validation for prediction of gefitinib sensitivity by epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer
… either of these two hotspot mutations. Therefore, we developed a … mutations 29 and conducted
a prospective cohort study to explore the prediction of gefitinib sensitivity in EGFR mutation…
a prospective cohort study to explore the prediction of gefitinib sensitivity in EGFR mutation…
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