[HTML][HTML] EGFR mutation and brain metastasis in pulmonary adenocarcinomas

DY Shin, CH Kim, S Park, HJ Baek, SH Yang - Journal of Thoracic …, 2014 - Elsevier
… of EGFR mutation with respect to brain metastases by using … between EGFR mutation status
and brain metastasis was … association between EGFR mutation and extracranial metastases (…

Frequent EGFR mutations in brain metastases of lung adenocarcinoma

S Matsumoto, K Takahashi, R Iwakawa… - … journal of cancer, 2006 - Wiley Online Library
… showed that all 6 cases with EGFR mutations in their metastatic brain tumors had the identical
mutations in the corresponding primary tumors. Thus, EGFR mutations are likely to be an …

EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer

AF Eichler, KT Kahle, DL Wang, VA Joshi… - Neuro …, 2010 - academic.oup.com
EGFR tyrosine kinase inhibitors (TKIs). The characteristics and behavior of brain metastases
… The longitudinal records of all NSCLC patients who underwent EGFR mutation screening at …

Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation

R Porta, JM Sanchez-Torres, L Paz-Ares… - European …, 2011 - Eur Respiratory Soc
brain. However, our study clearly shows that those patients with brain metastases and EGFR
mutations … All patients with EGFR mutations obtained benefit within the brain (82.4% with …

EGFR mutation status in brain metastases of non-small cell lung carcinoma

F Burel-Vandenbos, D Ambrosetti, M Coutts… - Journal of neuro …, 2013 - Springer
… [37] suggest that EGFR mutation status could … EGFR mutations in brain metastases could
be due to an increased ability of EGFR wild-type clones to metastasize to the CNS than EGFR-…

The role of EGFR mutation as a prognostic factor in survival after diagnosis of brain metastasis in non-small cell lung cancer: a systematic review and meta-analysis

WY Li, TT Zhao, HM Xu, ZN Wang, YY Xu, Y Han… - BMC cancer, 2019 - Springer
EGFR mutation is an important predictive factor linked to improved OS for NSCLC patients
with brain metastases… in the prognostic assessment of NSCLC patients with brain metastases. …

EGFR mutation status on brain metastases from non-small cell lung cancer

F Hsu, A De Caluwe, D Anderson, A Nichol, T Toriumi… - Lung Cancer, 2016 - Elsevier
… The purpose of this study was to examine the impact of EGFR mutations on the incidence
of brain metastases in patients with advanced non-small cell lung cancer (NSCLC). …

Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches

R Singh, EJ Lehrer, S Ko, J Peterson, Y Lou… - Radiotherapy and …, 2020 - Elsevier
… NSCLC patients with brain metastases harboring EGFR or ALK mutations have superior OS
compared to wild-type patients. No PFS or OS benefit was found with the addition of TKIs to …

Brain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancers

D Rangachari, N Yamaguchi, PA VanderLaan, E Folch… - Lung cancer, 2015 - Elsevier
… analysis for EGFR found 49% (20 of 41) of EGFR-mutated NSCLCs with … in the brain was
non-significantly longer in EGFR-mutated NSCLCs as compared to those with wild-type EGFR […

EGFR mutations in patients with brain metastases from lung cancer: Association with the efficacy of gefitinib

S Shimato, T Mitsudomi, T Kosaka, Y Yatabe… - Neuro …, 2006 - academic.oup.com
… Additionally, EGFR mutations have shown a strong association with gefitinib sensitivity …
brain metastases from NSCLC and evaluated the association of this efficacy with EGFR mutations