[HTML][HTML] Molecular epidemiology of lung cancer and geographic variations with special reference to EGFR mutations

T Mitsudomi - Translational lung cancer research, 2014 - ncbi.nlm.nih.gov
… sole risk factor for EGFR mutated lung cancer (OR for women … EGFR mutated NSCLC but
not with EGFR WT lung cancer (… polymorphisms and lung cancer with EGFR mutation. There …

EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma

AJJ Smits, JA Kummer, JWJ Hinrichs, GJM Herder… - Cellular oncology, 2012 - Springer
mutations. The overall frequency of EGFR mutations in lung adenocarcinomas in this West
… , whereas KRAS mutation frequency is higher than in any population described to date. …

Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma

EY Kim, EN Cho, HS Park, JY Hong, S Lim… - Cancer biology & …, 2016 - Taylor & Francis
… This study analyzed 61 cases of EGFR mutation positive lung adenocarcinoma using next-…
mutations and investigated clinical implication of compound EGFR mutations. Compound …

[HTML][HTML] EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

S Kobayashi, TJ Boggon, T Dayaram… - … England Journal of …, 2005 - Mass Medical Soc
… a patient with EGFR-mutant, gefitinib-responsive, advanced non–small-cell lung cancer who
… The DNA sequence of the EGFR gene in his tumor biopsy specimen at relapse revealed the …

Analyzing EGFR mutations and their association with clinicopathological characteristics and prognosis of patients with lung adenocarcinoma

X Zhou, L Cai, J Liu, X Hua, Y Zhang… - Oncology …, 2018 - spandidos-publications.com
… , EGFR mutations of patients with lung adenocarcinoma often go … significance of EGFR
mutations in lung adenocarcinoma and … study, EGFR mutations in lung adenocarcinoma patients …

EGFR mutations are detected comparably in cytologic and surgical pathology specimens of nonsmall cell lung cancer

JH Smouse, ES Cibas, PA Jänne… - Cancer …, 2009 - Wiley Online Library
… Janne has filed a patent claim for the analysis of EGFR mutations in lung cancer, and has
received honoraria (<$10,000) from Astra Zeneca and Roche and other remuneration from …

Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation

K Suda, K Tomizawa, T Mitsudomi - Cancer and Metastasis Reviews, 2010 - Springer
… for lung cancer patients with an EGFR mutation. In this review, we describe the features
of KRAS mutations in lung cancer and contrast these with the features of EGFR mutations. …

[HTML][HTML] The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis

YL Zhang, JQ Yuan, KF Wang, XH Fu, XR Han… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… The discovery of EGFR tyrosine kinase inhibitors (TKI) was regarded as a landmark finding
… of lung cancer [5–8]. Targeted EGFR-TKI first-line treatment of sensitizing EGFR mutations

[HTML][HTML] Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

T Zhang, B Wan, Y Zhao, C Li, H Liu, T Lv… - … lung cancer research, 2019 - ncbi.nlm.nih.gov
… In China, it is also the most common cancer and leading cause of cancer-related … (EGFR)
mutations. NSCLC harboring EGFR mutations constitutes about 10–20% of all lung cancer

Treatment of non-small cell lung cancer with EGFR-mutations

K Yoneda, N Imanishi, Y Ichiki, F Tanaka - Journal of UOEH, 2019 - jstage.jst.go.jp
… the tyrosine kinase of EGFR, which competitively inhibits ATP-… lung adenocarcinoma with
EGFRmutations (overall response rate [ORR], 71.2%), but not for that without EGFR-mutations (…