EGFR testing in lung cancer is ready for prime time
FR Hirsch, PA Bunn - The lancet oncology, 2009 - thelancet.com
… In conclusion, recent results support the use of EGFR mutations as a selection criterion
for EGFR TKIs as first-line therapy for patients with advanced NSCLC. However, …
for EGFR TKIs as first-line therapy for patients with advanced NSCLC. However, …
Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning
… learning model to predict EGFR mutation status in lung adenocarcinoma using non-invasive …
from 844 lung adenocarcinoma patients with pre-operative CT images, EGFR mutation and …
from 844 lung adenocarcinoma patients with pre-operative CT images, EGFR mutation and …
Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation
K Suda, K Tomizawa, T Mitsudomi - Cancer and Metastasis Reviews, 2010 - Springer
… for lung cancer patients with an EGFR mutation. In this review, we describe the features
of KRAS mutations in lung cancer and contrast these with the features of EGFR mutations. …
of KRAS mutations in lung cancer and contrast these with the features of EGFR mutations. …
[HTML][HTML] Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data
… Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung
adenocarcinoma with EGFR mutations. J Clin Oncol 2013; 31: 3327-3334, doi: 10.1200/JCO.…
adenocarcinoma with EGFR mutations. J Clin Oncol 2013; 31: 3327-3334, doi: 10.1200/JCO.…
Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes
… The degree and duration of response to epidermal growth factor receptor (EGFR) inhibitors
in EGFR mutated lung cancer are heterogeneous. We hypothesized that the concurrent …
in EGFR mutated lung cancer are heterogeneous. We hypothesized that the concurrent …
[HTML][HTML] Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21
JY Yu, SF Yu, SH Wang, H Bai, J Zhao, TT An… - … journal of cancer, 2016 - Springer
… lung adenocarcinoma harboring EGFR 19 del or L858R mutations, 532 received EGFR-TKI …
clinical outcomes of 532 lung adenocarcinoma patients harboring EGFR 19 del or L858R …
clinical outcomes of 532 lung adenocarcinoma patients harboring EGFR 19 del or L858R …
[HTML][HTML] EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
… S752 mutation (the initial EGFR mutation identified in our patient) and a second mutation in
… position 790 (T790M — the second EGFR mutation identified in our patient) were introduced …
… position 790 (T790M — the second EGFR mutation identified in our patient) were introduced …
[HTML][HTML] Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer
… EGFR mutations in patients, our understanding of the biology of these … EGFR mutations is
poor compared to classical mutations. In particular, clinical data focused on these mutations is …
poor compared to classical mutations. In particular, clinical data focused on these mutations is …
[HTML][HTML] Advances on EGFR mutation for lung cancer
G Metro, L Crinò - Translational lung cancer research, 2012 - ncbi.nlm.nih.gov
… lung cancer (NSCLC) and somatic activating mutations of the tyrosine kinase (TK) domain of
the epidermal growth factor receptor (EGFR… sensitivity to the reversible EGFR-TK inhibitors (-…
the epidermal growth factor receptor (EGFR… sensitivity to the reversible EGFR-TK inhibitors (-…
[HTML][HTML] Analyzing EGFR mutations and their association with clinicopathological characteristics and prognosis of patients with lung adenocarcinoma
X Zhou, L Cai, J Liu, X Hua, Y Zhang… - Oncology …, 2018 - spandidos-publications.com
… , EGFR mutations of patients with lung adenocarcinoma often go … significance of EGFR
mutations in lung adenocarcinoma and … study, EGFR mutations in lung adenocarcinoma patients …
mutations in lung adenocarcinoma and … study, EGFR mutations in lung adenocarcinoma patients …